24 citations,
May 2010 in “Hautarzt” Different hormones affect hair growth and conditions, with some causing hair loss and others promoting it.
23 citations,
June 2017 in “Rejuvenation Research” Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.
23 citations,
January 2001 in “Chemical & Pharmaceutical Bulletin” New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.
23 citations,
January 1998 in “Urological research” Castration and finasteride lower urinary oxalate in male rats, potentially treating urolithiasis.
20 citations,
November 2019 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
20 citations,
August 1987 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
19 citations,
June 2020 in “Animals” Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.
19 citations,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
19 citations,
January 2016 in “Biological & Pharmaceutical Bulletin” Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.
18 citations,
September 2016 in “International Journal of Molecular Sciences” Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.
18 citations,
January 2007 in “Pharmaceutical Biology” Citrullus colocynthis extract is effective for hair growth, comparable to minoxidil.
17 citations,
November 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” Finasteride helps brain function in rats with liver-related brain issues.
17 citations,
June 2012 in “European journal of medicinal chemistry” New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
15 citations,
January 2017 in “Experimental Neurology” Finasteride reduces movement issues in Parkinson's disease rats.
15 citations,
January 2013 in “Journal of Cutaneous and Aesthetic Surgery” The modified Direct Hair Transplantation method is effective for treating baldness with better graft survival and less damage than standard techniques.
14 citations,
January 2011 in “Urologia Internationalis” Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
12 citations,
June 2001 in “Bioorganic & Medicinal Chemistry” Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
12 citations,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.
12 citations,
January 1991 in “Archives of dermatological research” Male hormones control a specific gene in hamster skin, with different hormones having varying effects.
11 citations,
October 2020 in “Plant biotechnology journal” Overexpressing SIMK in alfalfa boosts root hair growth, nodule clustering, and shoot biomass.
10 citations,
December 2019 in “in Vivo” Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
10 citations,
May 2019 in “BMC Complementary and Alternative Medicine” The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
10 citations,
July 1997 in “Dermatologic Clinics” Laser hair transplantation can be effective but should be limited to small areas and requires more training to ensure safety and effectiveness.
9 citations,
May 2021 in “Molecules” New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
9 citations,
October 2013 in “PLOS ONE” Dutasteride works better than finasteride for preventing and treating prostate cancer.
9 citations,
August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
7 citations,
July 2019 in “Scientific Reports” Finasteride helps reduce heart enlargement in heart failure patients.
6 citations,
October 2007 in “Medical Hypotheses” Male pattern baldness might have evolved to help protect against prostate cancer by increasing UV radiation on the scalp.
5 citations,
June 2018 in “Records of Natural Products” Garden cress extract may help treat skin inflammation and androgen-related disorders.