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Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

The study created a new method to test drugs that affect hormone processing in skin.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Different enzymes are active in different parts of developing mouse organs.

RNA can be extracted from horsehair roots for analysis.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Some hair loss can be treated, especially in women due to nutrition, but some types remain untreatable.

Finasteride effectively reduces hair loss by decreasing androgen levels.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Finasteride negatively affects fish reproduction and gonadal development.

Dutasteride more effective for hair growth, but has more side effects than finasteride.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

Finasteride doesn't affect erections much, but may decrease libido in men.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Finasteride potentially treats hair loss by reducing DHT production.

Finasteride effectively treats baldness but may cause sexual side effects.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Ganoderma lucidum may help treat enlarged prostate in rats.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Compounds from the plant Mammea siamensis may help treat hair loss.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.