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Brepocitinib 30mg is most effective for moderate-to-severe alopecia areata, but ritlecitinib 50mg may offer a better balance of safety and effectiveness.

Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

5-alpha reductase inhibitors might worsen lung recovery in COVID-19 patients, suggesting a pause in their use.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

A blood pressure drug, diltiazem, may also help treat influenza.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Semecarpus anacardium leaf extracts may offer safe, effective cancer treatment alternatives.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Tadalafil is effective for treating urinary symptoms in men with BPH.

Finasteride effectively treats BPH but may increase sexual dysfunction risk.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.

The study found that the average age of women diagnosed with Frontal Fibrosing Alopecia in Argentina is higher than in other countries, but their symptoms are similar.

More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.

Hormonal therapies help treat female hair loss, but results are slow and vary.