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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Testosterone helps human pancreatic cells increase insulin release.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Korean and Caucasian men with male pattern baldness have different hair steroid levels.

Sebocytes play a key role in controlling androgen levels in human skin.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

Researchers made two new compounds that could be used for medicine.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

Finasteride doesn't affect ovulation in normal women.

Finasteride blocks progesterone's effect on absence seizures in rats.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Compound 15a was effective in inhibiting 5α-reductase.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Finasteride affects prostate weights and pituitary activity differently with age.

Certain Dibenzo derivatives may help treat prostate cancer.