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Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

New compounds may help treat prostate cancer by reducing cell growth.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

A PET-CT scan successfully located a hard-to-find Leydig cell tumor in a woman with hormonal symptoms.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.

DHT affects testicular development and regulates spermatogenesis in some fish.

High levels of testosterone and 5α-DHT can lead to cell death in cells important for hair growth.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.

Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

The normal human prostate does not significantly affect blood DHT levels.

Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.

Treatment during development affects hormone balance and sexual behavior in male rats.

Electro-acupuncture may help treat PCOS in rats by changing brain DNA methylation.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Certain gene variations increase male hair loss risk, influenced by hormone levels.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Testosterone's muscle-building effects do not require its conversion to DHT.

Finasteride affects prostate weights and pituitary activity differently with age.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.