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Spironolactone reduces the enzyme activity that converts testosterone to DHT, helping treat excessive hair growth in women.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Impure benzeneseleninic anhydride samples cause lower finasteride intermediate yields.

TRM21 helps control flavonoid production and root hair growth in Arabidopsis thaliana.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Stump-tailed macaque best for researching hair loss causes and treatments.

Finasteride can cause lasting sexual dysfunction, depression, and other side effects, needing more research for treatment.

Moringa seed oil may help prevent hair loss and promote hair growth.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Minoxidil effectively promotes hair regrowth in younger patients with small balding areas.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

Better hair loss models needed for research.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that hair biology is complex and there are still unanswered questions about hair loss and follicle changes.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride use changes brain chemicals, causing lasting sexual issues and anxiety/depression.