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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

Finasteride doesn't affect erections much, but may decrease libido in men.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Sebocytes play a key role in controlling androgen levels in human skin.

Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.

Finasteride improves hair loss in women with hyperandrogenism.

Dutasteride is more effective than finasteride for hair loss treatment.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

Four-amino acid part makes enzyme sensitive to finasteride.

Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

Plant-based treatments can effectively and safely treat hair loss.

Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.