Search
for

    Sort by

    Research 30 of 1000+

    1. Novel inhibitors of 5α-reductase Expert Opinion on Therapeutic Patents · 2002 · 20 citations
    2. A concise review- Development of an analytical method and validation of dutasteride Current Trends in Pharmacy and Pharmaceutical Chemistry · 2025
    3. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    4. Species Differences in Prostatic Steroid 5<i>α</i>-Reductases of Rat, Dog, and Human Endocrinology · 1985 · 193 citations
    5. Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond Journal of Chemical Crystallography · 2008 · 2 citations
    6. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    7. Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase Bioorganic & Medicinal Chemistry · 1997 · 5 citations
    8. 5α-Reductase Inhibitors, Chemical and Clinical Models Steroids · 1998 · 17 citations
    9. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    10. Alopecia - the search for novel agents continues Expert Opinion on Therapeutic Patents · 1997 · 11 citations
    11. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    12. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    13. In Vivo Time-Dependent Inhibition of Human Steroid 5a-Reductase by Finasteride Journal of Pharmaceutical Sciences · 1996 · 29 citations
    14. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations
    15. Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase Journal of Medicinal Chemistry · 1993 · 89 citations
    16. Synthesis of N-Substituted 3-Oxo-17b- carboxamide-4-aza-5a-androstanes and the Tautomerism of 3-Oxo-4-aza-5-androstenes Heterocycles · 1998 · 4 citations
    17. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    18. Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne Journal of Dermatology · 2010 · 8 citations
    19. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    20. Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears. Endocrinology · 1996 · 8 citations
    21. Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase Helvetica Chimica Acta · 1995 · 8 citations
    22. Investigation of intermolecular interactions in finasteride drug crystals in view of X-ray and Hirshfeld surface analysis Journal of Molecular Structure · 2015 · 16 citations
    23. Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2006 · 14 citations
    24. Finasteride for prostatic disease: an updated and comprehensive review Expert opinion on drug metabolism & toxicology · 2008 · 14 citations
    25. Recent advances in thiasteroids chemistry Steroids · 2006 · 37 citations
    26. In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands Current Enzyme Inhibition · 2020
    27. 5-α-Reductase inhibitors for prostate cancer chemoprevention: an updated Cochrane systematic review BJUI · 2010 · 44 citations
    28. Pharmacophore and Atom Based 3D QSAR Studies on the Novel 5-Alpha-Reductase Inhibitors Indian Journal of Pharmaceutical Education · 2018 · 2 citations
    29. The multiple uses of azelaic acid in dermatology: mechanism of action, preparations, and potential therapeutic applications Postępy Dermatologii i Alergologii · 2023
    30. Molecular Interactions of New Pregnenedione Derivatives Chemical and Pharmaceutical Bulletin · 2003 · 20 citations