10 citations,
January 2017 in “Journal of Evidence-Based Complementary & Alternative Medicine” Some vegetables from Northern Thailand show promise for health benefits, including hair loss treatment and antioxidant properties.
July 2020 in “European urology open science” Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.
26 citations,
September 2018 in “Neurobiology of Disease” Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.
12 citations,
January 2018 in “Journal of Drug Delivery Science and Technology” The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
11 citations,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
July 2024 in “Biological and Pharmaceutical Bulletin” Licorice extract helps hair growth and may treat hair loss.
November 2023 in “Scientific reports” The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.
22 citations,
October 2001 in “Biochemical Pharmacology” GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
47 citations,
January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
5 citations,
July 2021 in “Endocrinology, diabetes & metabolism” Glioblastoma cells can make androgens, which might help the tumor grow.
4 citations,
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February 1999 in “PubMed” Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.
11 citations,
September 1997 in “Archives of Dermatology” Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.
June 2024 in “Reviews on Recent Clinical Trials” Finasteride and dutasteride may cause metabolic issues like liver disease and diabetes.
8 citations,
July 2021 in “F1000Research” Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
May 2024 in “Scientific African” Three natural compounds from Ghanaian plants may help treat BPH and alopecia.
November 2022 in “International Journal of Applied Pharmaceutics” Ergostadienol from Moringa seed oil may help prevent hair loss.
70 citations,
September 2017 in “Expert opinion on therapeutic patents” The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
1 citations,
February 2023 in “Plants” BB4CMU rice bran oil may help treat hair loss and gray hair.
October 2022 in “Frontiers in Bioengineering and Biotechnology” Bioengineered nanoparticles can effectively treat hair loss by targeting specific enzymes and receptors.
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
1 citations,
August 2018 in “Journal of The American Academy of Dermatology” Patients with melanoma who saw dermatologists and were from higher-income areas were more likely to have follow-up visits, which was linked to lower mortality.
5 citations,
July 1994 in “PubMed” Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
12 citations,
January 2018 in “Pharmacology & pharmacy” Pumpkin seed products may help improve prostate and bladder health by blocking certain enzymes and hormone receptors.
17 citations,
October 2003 in “Brazilian Journal of Medical and Biological Research” The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.
September 2024 in “Fitoterapia” Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.
1 citations,
January 2023 in “PubMed” Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.
4 citations,
August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
11 citations,
August 2019 in “BMJ” Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.