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The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Twice-weekly 5 mg betamethasone helps hair regrowth in alopecia areata.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

Low-dose finasteride effectively reduces hirsutism without serious side-effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Dutasteride may protect the brain in early Parkinson's disease.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

A3B5 can reduce skin pigmentation and slow melanoma growth.

A new method was developed to make finasteride for treating hair loss.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.

Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.

Finasteride 2.5 mg/day can effectively treat female hair loss.

Syphilitic alopecia, linked to syphilis and high-risk sexual behavior, improves with penicillin treatment.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride doesn't harm bone density in older men with BPH.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride may cause kidney damage.