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New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Physical activity, height, and smoking affect prostate cancer risk.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

Eurycoma longifolia extract may help increase testosterone levels and reduce andropause symptoms.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Tiny particles improved delivery of hair loss treatments to hair follicles, with lipid-based particles performing best.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Eosinophilia-myalgia syndrome, linked to contaminated L-tryptophan supplements, caused severe symptoms and some deaths, with long-term effects in survivors.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Some women with excess hair growth have a hormone condition that can't be diagnosed by blood or urine tests alone.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride reduces movement issues in Parkinson's disease rats.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Hura crepitans and its compound daphne factor F3 may help treat hair loss by blocking a specific hair growth inhibitor.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

New tests detect finasteride and dutasteride in urine quickly and easily.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

A gene called Gk5 controls lipid production in the skin and affects hair growth.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

A 5% minoxidil spray could effectively treat male baldness with fewer side effects and better patient comfort.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.