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Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.

Treatments for Frontal Fibrosing Alopecia have not been proven effective.

Combination therapy with steroids and pimecrolimus improved or stabilized hair loss in most patients with Frontal Fibrosing Alopecia, who also had a high rate of hypothyroidism.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Hair and skin can regenerate without bulge stem cells due to other compensating cells.

Setipiprant may reduce inflammation by blocking an enzyme called aldose reductase.

Lower vitamin D levels might be linked to more severe alopecia areata, but more research is needed to understand if vitamin D can help treat it.

Fluridil promotes hair growth safely and effectively for androgenetic alopecia.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

A woman's hair loss during Hepatitis C treatment with PEG-INF-a-2a and Ribavirin was reversible after stopping the medication.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

PCOS requires personalized treatment to improve life quality and reduce health risks.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

A boy with severe Vitamin D-resistant rickets did not respond to treatment and lacked a common symptom, suggesting a need for alternative treatments.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.

Minoxidil effectively lowers blood pressure and initially increases plasma renin activity without raising aldosterone levels.

Vitexin Compound 1 may help reduce skin aging caused by UVA light.

The document says that common skin conditions in adult women can be treated effectively, with acne being the most common and early-detected melanoma having a high survival rate.

Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.

Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.

Rubbing calcipotriol on the skin works better than taking vitamin D pills for treating mild to moderate alopecia areata.

Scalp hair sweating is a significant predictor of hair cortisol levels.

Tretinoin gel is safe for sun exposure, but tacalcitol doesn't significantly improve non-segmental vitiligo.

Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.