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    Research 661–690 of 1000+

    1. Inhibition of 5α‐Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice Alcoholism Clinical and Experimental Research · 2008 · 49 citations
    2. Actions of 5α-reductase inhibitors on the epididymis Molecular and Cellular Endocrinology · 2006 · 48 citations
    3. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing theneu oncogene under the control of the bovine keratin 5 promoter Molecular Carcinogenesis · 1998 · 47 citations
    4. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations
    5. Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss Journal of The American Academy of Dermatology · 1999 · 46 citations
    6. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations
    7. Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-<i>β</i>-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments Oxidative medicine and cellular longevity · 2016 · 43 citations
    8. Effect of finasteride 5 mg (Proscar) on acne and alopecia in female patients with normal serum levels of free testosterone Gynecological Endocrinology · 2007 · 43 citations
    9. Efficacy of 5% Minoxidil versus Combined 5% Minoxidil and 0.01% Tretinoin for Male Pattern Hair Loss American Journal of Clinical Dermatology · 2007 · 43 citations
    10. β-catenin-mediated hair growth induction effect of 3,4,5-tri-O-caffeoylquinic acid Aging · 2019 · 42 citations
    11. Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats Gene · 2015 · 42 citations
    12. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice Psychoneuroendocrinology · 2012 · 42 citations
    13. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    14. Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures Plastic and Reconstructive Surgery · 2013 · 39 citations
    15. More about X‐linked testicular feminization of the mouse as a noninducible (i<sup>s</sup>) mutation of a regulatory locus: 5α‐androstan‐3α‐17ß‐diol as the true inducer of kidney alcohol dehydrogenase and ß‐glucuronidase Clinical genetics · 1971 · 38 citations
    16. Effect of dutasteride 0.5 mg/d in men with androgenetic alopecia recalcitrant to finasteride International Journal of Dermatology · 2014 · 36 citations
    17. Finasteride: the first 5 alpha-reductase inhibitor. PubMed · 1993 · 34 citations
    18. Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015 · 33 citations
    19. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    20. Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia Expert Opinion on Investigational Drugs · 1999 · 32 citations
    21. Smad1 and 5 but Not Smad8 Establish Stem Cell Quiescence Which Is Critical to Transform the Premature Hair Follicle During Morphogenesis Toward the Postnatal State Stem Cells · 2013 · 31 citations
    22. The Effect of 5 -Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008 · 31 citations
    23. Randomized clinical trial comparing 5% and 1% topical minoxidil for the treatment of androgenetic alopecia in Japanese men Journal of Dermatology · 2009 · 29 citations
    24. Ethanol‐induced elevation of 3α‐hydroxy‐5α‐pregnan‐20‐one does not modulate motor incoordination in rats Alcoholism Clinical and Experimental Research · 2004 · 26 citations
    25. Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing Diabetes · 2021 · 25 citations
    26. The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers The Journal of Clinical Pharmacology · 1989 · 25 citations
    27. The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase? Journal of neuroendocrinology · 2013 · 24 citations
    28. Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes <i>In Vitro</i> Hormone and metabolic research · 2007 · 24 citations
    29. Finasteride: The First 5α-Reductase Inhibitor Pharmacotherapy · 1993 · 23 citations
    30. Safety of 5α-reductase inhibitors and spironolactone in breast cancer patients receiving endocrine therapies Breast Cancer Research and Treatment · 2018 · 22 citations