research Exploring the Neural Mechanisms of Finasteride: A Proteomic Analysis in the Nucleus Accumbens
Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
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research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts
Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.
research Gemcitabine in Combination with Vinorelbine in Elderly Patients with Anthracycline- and Taxane-Pretreated Metastatic Breast Cancer
The combination of gemcitabine and vinorelbine is effective and safe for treating elderly patients with advanced breast cancer previously treated with anthracyclines and taxanes.
research Sex Differences in the Hypothalamic–Pituitary–Adrenal Axis’ Response to Stress: An Important Role for Gonadal Hormones
Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Iron Deficiency Anemia Pruritus: A Review with Proposed Mechanisms of Action
Iron deficiency anemia can cause itching, which often improves with iron supplements.
research A Subpopulation of Itch-Sensing Neurons Marked by Ret and Somatostatin Expression
Scientists found a specific group of itch-sensing nerve cells in mice important for feeling itch but not for sensing heat or touch.
research Clinical Review of Ejaculatory Dysfunction
The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.
research Effect of Flutamide and Two Novel Synthetic Steroids on GABA, Glutamine, and Some Oxidative Stress Markers in Rat Brain and Prostate
Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Current Prospective in the Management of Depression Using Off-Label Drugs and Advanced Drugs
New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
research Quantitative Determination of Nutraceuticals in Matured Unripe Fruits of Three Edible Musa Species Using GC-MS
Unripe fruits of three banana species have many health-boosting compounds useful for medicine.
research Alopecia Areata: A Review on Diagnosis, Immunological Etiopathogenesis, and Treatment Options
The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.
research Clinical Guidance on the Monitoring and Management of Trastuzumab Deruxtecan (T-DXd)-Related Adverse Events: Insights from an Asia-Pacific Multidisciplinary Panel
Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.
research Genus Thuja: A Comprehensive Review on Botany, Traditional Uses, Pharmacological Activities, and Phytochemistry
Thuja plants have medicinal properties and potential for developing new therapies.
research Novel Effect of Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) on Hair Follicle Cells Proliferation and Hair Growth
HAPLN1 can promote hair growth and may help treat hair loss.
research Men's Health
The document concludes that various drugs for men's health issues are in development, with treatments for sexual dysfunction and prostate conditions being the most advanced.
research Clinico-Mycological Profile and Trichoscopic Findings Among Pediatric Tinea Capitis Patients: A Cross-Sectional Study from Northern India
Trichoscopy is a valuable, quick, and non-invasive tool for diagnosing tinea capitis in children.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research COVID-19 and Hypopituitarism
COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
research Revitalizing Your Skin: The Power of Microneedling with PRP for Pigmentation Reduction
Microneedling with PRP effectively reduces facial pigmentation with minimal side effects.
research Efficacy of Korean Red Ginseng in the Treatment of Atopic Dermatitis
Korean Red Ginseng may improve skin condition and reduce allergy markers in atopic dermatitis patients.
research Author Response for 'The Comparative Effects Between Long-Term and Short-Term Treatment of Finasteride on Anxiety-Like and Depression-Like Behaviors in Early Senescent Male Rats'
research Drug Repositioning Using In Silico Compound Profiling
Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.
research Skin Manifestations of Chronic Kidney Disease
People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Skin Manifestations of Chronic Kidney Disease
Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.
research Bendamustine in Indolent Non-Hodgkin's Lymphoma: A Practice Guide for Patient Management
Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.
research Cluster Headache: Acute and Prophylactic Therapy
Sumatriptan injections, high-flow oxygen, and verapamil effectively treat cluster headaches.
research Chemotherapy-Induced Dermatological Toxicity: Frequencies and Impact on Quality of Life in Women’s Cancers. Results of a Prospective Study
Chemotherapy often causes skin, nail, and hair side effects, significantly impacting quality of life.