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The meeting focused on understanding, diagnosing, and finding treatments for irreversible hair loss diseases.

Scalp cooling can prevent hair loss in 65% of chemotherapy patients, especially effective in breast cancer patients and certain chemotherapy types.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

5% minoxidil works better for hair growth and density, with minor irritation.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

5% and 2% minoxidil solutions effectively promote hair growth and reduce hair loss, with 5% being slightly more effective but having more side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Testosterone's muscle-building effects do not require its conversion to DHT.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

5% minoxidil foam once daily works as well as 2% minoxidil solution twice daily for female hair growth and is more convenient.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Finasteride improves hair density and thickness in women with hair loss.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.