124 citations,
January 1993 in “The Prostate” Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.
100 citations,
September 1999 in “British Journal of Dermatology” The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.
51 citations,
May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
47 citations,
July 2009 in “Journal of Biological Chemistry” Finasteride helps treat hair loss and prostate enlargement by blocking a specific enzyme.
46 citations,
March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
36 citations,
June 2014 in “International Journal of Dermatology” Dutasteride helps hair growth in those unresponsive to finasteride, but may cause more sexual dysfunction.
33 citations,
April 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity” 5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.
![Synthesis of 5,6,6-[2H3]Finasteride and Quantitative Determination of Finasteride in Human Plasma at Picogram Level by an Isotope-Dilution Mass Spectrometric Method](/images/research/0026b639-99a8-455a-a986-c39aa65abfa9/small/2087.jpg)
20 citations,
December 1995 in “Journal of Chromatography B: Biomedical Sciences and Applications” Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.
18 citations,
January 2003 in “Gynecological Endocrinology” Low-dose finasteride effectively reduces hirsutism without serious side-effects.
16 citations,
August 2014 in “Archives of Pharmacal Research” Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.