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Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Photodynamic therapy with methyl 5-aminolevulinic acid is ineffective for treating alopecia totalis.

PRP combined with minoxidil is the most effective and safe treatment for male pattern baldness.

Dutasteride is more efficient than finasteride, but individual results vary.

The study concluded that AAI and DAA are forms of the same disease, with different symptoms in men and women, and that corticosteroid treatment is effective.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

TGF-β1 increases androgen receptor activity in hair loss, but Hic-5/ARA55 can counter this effect.

A 5-year-old girl's scalp scarring and hair loss from lupus improved with specific medications.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Minoxidil 5% caused skin discoloration in a man using it for hair loss.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Gene differences may affect baldness treatment response in Korean men.

Finasteride helps protect brain in old male rats.

Adding low-level light therapy to minoxidil improves hair growth and patient satisfaction.

Imiquimod 5% cream may not work for treating scrotal extramammary Paget disease.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Minoxidil 5% solution significantly improved hair density in a girl with loose anagen hair syndrome over 28 months, with no side effects.

The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

A new mouse mutation causes skin and hair defects due to a gene change.