research 5-Alpha-Reductase Deficiency in a Saudi Girl
A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
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research Effectiveness of Chuzhi Shengfa Tablets Combined with Ketoconazole Shampoo and Chuzhi Shengfa Tablets Combined with 5% Minoxidil Foam in the Treatment of Male Androgenetic Alopecia
Combining Chuzhi Shengfa Tablets with ketoconazole shampoo or 5% minoxidil foam effectively promotes hair growth in men.
research Inhibition of 5-Alpha Reductase Attenuates Cardiac Oxidative Damage in Obese and Aging Male Rats via the Enhancement of Antioxidants and the p53 Protein Suppression
Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.
research Effect of 5-Alpha Reductase Inhibitors in Animal Models of Parkinson's Disease
5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
research Risk of Estrogen-Driven Malignancies in Females on 5-Alpha Reductase Inhibitors
Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.
research 18-β-Glycyrrhetinic Acid Promotes Hair Growth by Stimulating the Proliferation of Dermal Papilla Cells and Outer Root Sheath Cells, and Extends the Anagen Phase by Inhibiting 5α-Reductase
Licorice extract helps hair growth and may treat hair loss.
research Long-Term Treatment with a 5-Alpha-Reductase Inhibitor Alleviates Depression-Like Behavior in Obese Male Rats
Long-term finasteride treatment reduces depression and brain issues in obese male rats.
research Differential Association Between Cumulative Dose of 5α-Reductase Inhibitors and Mortality
Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.
research Recent Trends in Nanocarrier Formulations of Actives Beyond Minoxidil and 5-Alpha Reductase Inhibitors in Androgenetic Alopecia Management: A Systematic Review
Nanocarrier-based treatments show promise for better hair growth in androgenetic alopecia but need more research.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction, growth, and metabolism.
research Comparison of Efficacy of Autologous Platelet Rich Plasma Therapy With 5% Topical Minoxidil Spray in Treating Alopecia Areata: A Head-to-Head Assessment of Novel Approaches
Monthly PRP therapy is more effective than daily minoxidil for alopecia areata.
research A Comparative Study on the Efficacy and Safety of 10% Topical Minoxidil Versus 5% Topical Minoxidil in the Treatment of Male Pattern Hair Loss
10% minoxidil improves frontal hair count more than 5% but has more side effects.
research Association of 5α-Reductase Inhibitors With Depression and Suicide: A Mini Systematic Review and Meta-Analysis
Drugs for prostate enlargement and hair loss were not linked to increased risk of depression or suicide.
research Congenital Triangular Alopecia: A Case of Effective Response with 5% Topical Minoxidil in a Male Adolescent
5% topical minoxidil effectively treated a boy's congenital triangular alopecia without side effects.
research Emerging and Traditional 5-Alpha Reductase Inhibitors and Androgen Receptor Antagonists for Male Androgenetic Alopecia
New treatments for male hair loss are being explored to improve effectiveness and reduce side effects.
research How Do 5-Alpha-Reductase Inhibitors Change PSA Density in Patients on Active Surveillance?
5-alpha-reductase inhibitors lower PSA density but higher PSA density indicates disease progression.
research Methylation of SRD5A2 in the Blood as a Novel Biomarker to Predict Sensitivity to 5-ARI Treatment
SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.
research Sexual Dysfunction With 5-Alpha-Reductase Inhibitor Therapy for Androgenetic Alopecia: A Global Propensity Score Matched Retrospective Cohort Study
Taking medication for hair loss might cause sexual problems.
research Focal Neurotoxicity Associated With Topical 5-Fluorouracil
Topical 5-Fluorouracil can rarely cause nerve damage, especially in people with a certain genetic deficiency.
research The Effect of 5-Alpha Reductase Inhibitor on Male Reproductive Function
5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
research Effects of Solvent System and Storage Condition on Chemical Stability of 5α-Reductase Inhibitor Compounds in Tectona Grandis Leaf Extracts
Store Tectona grandis leaf extracts in slightly acidic, light-protected conditions for best stability.
research Investigator-Blinded, Controlled, and Randomized Comparative Study on 1565 Nm Non-Ablative Fractional Laser Versus 5% Minoxidil for Treatment of Androgenetic Alopecia
The 1565 nm non-ablative fractional laser is more effective and satisfying than 5% minoxidil for treating hair loss.
research Phytotherapeutic Alternatives to the Use of Finasteride and Dutasteride as 5-Alpha Reductase Inhibitors in the Treatment of Androgenetic Alopecia: A Review
Some plant-based products might treat hair loss with fewer side effects than current medications.
research Efficacy of Platelet-Rich Plasma Versus 5% Topical Minoxidil for the Treatment of Androgenetic Alopecia
PRP therapy is more effective than minoxidil for treating hair loss from androgenetic alopecia.
research Adverse Effects of the 5-Alpha-Reductase Inhibitor Finasteride on Daphnia Magna: Endocrine System and Lipid Metabolism Disruption
Finasteride harms Daphnia magna's reproduction and metabolism.
research 5 Alpha-Reductase Inhibitory Potential of Solanum Nigrum for Alopecia Management
Solanum nigrum may help treat hair loss.
research Fructus Psoraleae Treating Androgenetic Alopecia Through 5-Alpha Reductase Inhibition and Nrf2-Keap1 Pathway
Fructus Psoraleae may help treat hair loss by inhibiting 5-α reductase and affecting the Nrf2-Keap1 pathway.
research pH Stimulus-Responsive Hybrid Nanoparticles: A System Designed for Follicular Delivery of Brazilian Plant-Derived 5-Alpha-Reductase Enzyme Inhibitors
New nanoparticles deliver plant extracts to hair follicles to treat conditions like hair loss and acne.
research Chronic Exposure of 5-Alpha Reductase Inhibitor in Young Male Rats Induces Metabolic Disturbance and Depressive-Like Behaviors
Long-term use of a drug for hair loss and prostate issues can cause metabolic problems and depression-like behavior in young male rats.
research Efficacy and Safety of Topical 5% Azelaic Acid Solution Versus 2% Minoxidil Solution in the Treatment of Female Pattern Hair Loss
5% Azelaic acid is as effective as 2% Minoxidil for female pattern hair loss and could be an alternative for those allergic to Minoxidil or pregnant.