research Interconnected Polymers Technology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions
A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
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research Theoretical Evaluation of Interaction of Some Dibenzo Derivatives on Both Androgen Receptor and 5-Alpha-Reductase Enzyme
Certain Dibenzo derivatives may help treat prostate cancer.
research Minoxidil Acts as an Antiandrogen: A Study of 5α-Reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line
Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.
research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%
A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
research Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism
Finasteride causes abnormal growth in male mice cells at high doses.
research Comparative Study of Efficacy of Platelet Rich Plasma Versus Minoxidil (5%-10%) in the Treatment of Androgenetic Alopecia in Males
PRP is more effective than minoxidil for treating male pattern baldness.
research Urtica Dioica Extract Downregulates the Gene Expression of 5α-Reductase Type II in HaCaT Cells: Possible Implications Against Androgenic Skin Diseases
Urtica dioica extract may help treat androgenic skin diseases by reducing a specific gene's activity.
research The Effectiveness of 0.03% Bimatoprost Solution vs Minoxidil 5% in Androgenic Alopecia
research Alopecia: A Google Trends Analysis of the Past 5 Years (2018-2023)
Google trends show varying interest in alopecia types, but it's not a reliable health measure.
research Efficacy of Topical Finasteride 0.25% With Minoxidil 5% Versus Topical Minoxidil 5% Alone in the Treatment of Male Pattern Androgenic Alopecia
Combining finasteride with minoxidil is more effective for male hair loss than using minoxidil alone.
research Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia
research Evaluation of Platelet-Rich Plasma Versus Topical Minoxidil (5%) in Combination with Oral Finasteride for the Treatment of Androgenic Alopecia
PRP with finasteride is better for hair regrowth than minoxidil with finasteride.
research Intraoperative Iris Behavior During Phacoemulsification Maneuvers in Rabbits Treated with Selective Alpha-1 Blocker, 5-Alpha-Reductase Inhibitor, or Anxiolytic Medication
Tamsulosin increases the risk of floppy iris during eye surgery.
research Age-Related Progression of Androgenetic Alopecia: Statistical Analysis in 5,372 Japanese Men
research Risk of Age-Related Macular Degeneration in Men Receiving 5α-Reductase Inhibitors: A Population-Based Cohort Study
Men taking dutasteride may have a higher risk of age-related macular degeneration.
![Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment](/images/research/693e7bf6-2325-4ddc-a20f-3470db9f4516/small/25627.jpg)
research Discovery of (2S)-N-(6-Cyano-5-(Trifluoromethyl)Pyridin-3-Yl)-3-(6-(4-Cyanophenyl)-3,6-Diazabicyclo[3.1.1]Heptan-3-Yl)-2-Hydroxy-2-Methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment
A new topical treatment for hair loss shows strong hair growth effects with low toxicity.
research MRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
research Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men
Cetosomal minoxidil is safer and as effective as alcohol-based minoxidil for male hair loss treatment.
research Hair And Nail Disorders In Children With Fitzpatrick Skin Type V
Children with darker skin can have various hair and nail issues.
research Inhibitory Effects of Pueraria Mirifica Aqueous Extracts on 5α-Reductase and Prostate Histomorphometry in Testosterone-Induced Benign Prostatic Hyperplasia Sprague Dawley Rats
Pueraria mirifica extract may help treat benign prostatic hyperplasia.
research Localized Hypotrichosis Type 1 Due to Intragenic Deletion of Exons 5-8 in Desmoglein Gene in a Neonate from Indian Family
A baby from an Indian family had a rare genetic disorder causing no scalp or body hair due to a specific gene deletion.
research Comparative Efficacy of Topical Finasteride (0.25%) in Combination With Minoxidil (5%) Against 5% Minoxidil or 0.25% Finasteride Alone in Male Androgenetic Alopecia: A Pilot, Randomized Open-Label Study
Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.
research Persistent Virilization and Vasomotor Symptoms in a Transman 5 Years Post Testosterone Withdrawal
A transman experienced lasting virilization symptoms after stopping testosterone, which were resolved with estradiol treatment.
research Vibrational Spectroscopic Investigation and Molecular Structure of a 5α-Reductase Inhibitor: Finasteride
Finasteride's molecular properties and active sites were identified using computational methods.
research Development of Microemulsions Containing Carthamus Tinctorius Extract for 5α-Reductase Inhibition
A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
research The Efficacy of Ostrich Antibodies to Dihydrotestosterone and 5α-Reductase in the Restoration of Hair Growth
Ostrich antibodies can help restore hair growth in people with a specific type of hair loss, increasing hair count by 71% on average.
research The Skin Findings of Pregnant Women and Our Treatment Choices: A Turkish Experience Over a 5-Year Survey
Turkish pregnant women commonly experienced skin issues like itching and acne, and doctors mainly used topical treatments due to safety concerns during pregnancy.
research Comparison of the Efficacy and Safety of Topical 5% Minoxidil Solution Alone and in Combination with 0.05% Betamethasone Dipropionate Cream in the Treatment of Alopecia Areata
The combination of minoxidil and betamethasone is more effective for hair regrowth than minoxidil alone.
research Comparison of Microneedling With Platelet Rich Plasma Versus Minoxidil (5%) Plus Finasteride (0.1%) Topical Therapy in Androgenetic Alopecia: A Randomised Clinical Study
Microneedling with PRP is as effective and safe as minoxidil+finasteride for treating hair loss.
research In Vitro Evaluation of Skin Distribution and Human Dermal Papilla Cells Proliferation for Minoxidil 5% Topical Lotion Hydrogel
The new minoxidil hydrogel is a promising alternative for hair loss treatment, with similar effectiveness and less skin irritation.