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Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

A man with KID syndrome developed a rare cancer in a long-term skin infection.

Finasteride doesn't affect sleep spindles in men.

A woman's pelvic pain and bleeding led to finding and successfully treating a rare benign tumor in her reproductive system.

Adding aripiprazole to the treatment improved hair-pulling symptoms in a teenager.

Phytoconstituents from Cyperus Rotundus may help treat hirsutism by interacting with the 5 α reductase enzyme.

High temperatures, acidic conditions, and too much coconut oil damage hair, while a pH of 5 to 7 keeps it healthy.

5% minoxidil foam helps women with thinning hair.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Testosterone's muscle-building effects do not require its conversion to DHT.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Some herbs show promise as antiandrogenic agents.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

New compounds may soon be tested to treat excessive hair growth in women.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Minoxidil foam 5% effectively treats hair loss in both frontal and vertex scalp regions.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Hair loss drugs may cause sexual issues and infertility in men.

A benign tumor developed at a girl's BCG vaccination site, not previously linked to the vaccine.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.