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    Research 181–210 of 1000+

    1. Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study Precision medicine and clinical omics · 2022 · 3 citations
    2. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    3. The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer 2008 · 108 citations
    4. In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors The Journal of Steroid Biochemistry and Molecular Biology · 2008 · 27 citations
    5. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    6. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    7. Intraoperative Iris Behavior during Phacoemulsification Maneuvers in Rabbits Treated with Selective α1-Blocker, 5α-Reductase Inhibitor, or Anxiolytic Medication Journal of Personalized Medicine · 2024
    8. A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives Molecules · 2020 · 2 citations
    9. Establishment of type II 5α-reductase over-expressing cell line as an inhibitor screening model 2007 · 12 citations
    10. Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells Toxicology in Vitro · 2025 · 1 citations
    11. Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study Life · 2023
    12. Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo Archives of Dermatological Research · 2021 · 18 citations
    13. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019 · 101 citations
    14. 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG) from Polygonum multiflorum Thunb.: A Systematic Review on Anti-Aging International Journal of Molecular Sciences · 2025 · 3 citations
    15. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    16. Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice International Journal of Molecular Sciences · 2023
    17. Hair Growth-Promoting Effects of a Multi-Targeted Cosmetic Formulation Containing PYGL, DP2, and 15-PGDH Inhibitors Developed Using AI-Based DeepZema® in Androgenetic Alopecia: A 24-Week Randomized Controlled Trial Cosmetics · 2026
    18. The clinical applications of five-alpha reductase inhibitors. Canadian Journal of Urology · 2021 · 2 citations
    19. Development of a new gas chromatography–mass spectrometry (GC–MS) methodology for the evaluation of 5α-reductase activity Talanta · 2013 · 17 citations
    20. Is the “Comb Over” Dying? A Mouse Model for Male Pattern Baldness (Androgenic Alopecia) Endocrinology · 2010 · 3 citations
    21. Treatment of Lichen Planopilaris and Frontal Fibrosing Alopecia: A Retrospective, Real-Life Analysis in a Tertiary Center in Germany Journal of Clinical Medicine · 2024
    22. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations
    23. Hormone therapy in acne Indian Journal of Dermatology, Venereology and Leprology · 2013 · 24 citations
    24. 1424 METHYLATION AND DECREASED EXPRESSION OF 5-ALPHA REDUCTASE 2 IN HUMAN PROSATE SAMPLES: IMPLICATIONS FOR RESISTANCE TO THERAPY FOR BPH The Journal of Urology · 2010
    25. 5α-reductase inhibitors impact prognosis of urothelial carcinoma BMC Cancer · 2020 · 23 citations
    26. Inhibition of Inflammatory Gene Expression in Keratinocytes Using a Composition Containing Carnitine, Thioctic Acid and Saw Palmetto Extract Evidence-based Complementary and Alternative Medicine · 2009 · 22 citations
    27. Upregulation of mir-1199-5p is associated with reduced type 2 5-α reductase expression in benign prostatic hyperplasia BMC Urology · 2022 · 6 citations
    28. Hair: What is New in Diagnosis and Management? Dermatologic Clinics · 2012 · 46 citations
    29. 5α-Reduced glucocorticoids: a story of natural selection Journal of Endocrinology · 2011 · 46 citations
    30. Pharmacophore Modeling and Three Dimensional Database Searching for Drug Design Using Catalyst: Recent Advances Current Medicinal Chemistry · 2004 · 153 citations