Search
for

    Sort by

    Research 61–90 of 1000+

    1. Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium(III) chloride: Synthesis of 17α-propyl-17β-hydroxy-4-androsten-3-one, an androgen receptor antagonist Tetrahedron Letters · 1994 · 14 citations
    2. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations
    3. Comparison of Finasteride (Proscar®) and Serenoa repens (Permixon®) in the Inhibition of 5-Alpha Reductase in Healthy Male Volunteers European Urology · 1994 · 73 citations
    4. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    5. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    6. Consequences of steroid-5α-reductase deficiency and inhibition in vertebrates General and Comparative Endocrinology · 2020 · 21 citations
    7. The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases Advances in Urology · 2011 · 218 citations
    8. 9 Role of 5α-reductase in health and disease Baillière's clinical endocrinology and metabolism · 1994 · 101 citations
    9. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. The Journal of Clinical Endocrinology and Metabolism · 1994 · 59 citations
    10. Side Effects of 5‐Alpha Reductase Inhibitors: A Comprehensive Review Sexual medicine reviews · 2013 · 35 citations
    11. Hair growth effects of oral administration of finasteride, a steroid 5 alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque. The Journal of Clinical Endocrinology and Metabolism · 1992 · 34 citations
    12. Physiopathological role of the enzymatic complex 5α-reductase and 3α/β-hydroxysteroid oxidoreductase in the generation of progesterone and testosterone neuroactive metabolites Frontiers in Neuroendocrinology · 2020 · 18 citations
    13. Rat steroid 5α-reductase kinetic characteristics: Extreme pH-dependency of the type II isozyme in prostate and epididymis homogenates The Journal of Steroid Biochemistry and Molecular Biology · 1995 · 13 citations
    14. Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. 1996 · 11 citations
    15. Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target Journal of Medicinal Chemistry · 2021 · 3 citations
    16. Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD) Journal of Steroid Biochemistry · 1990 · 3 citations
    17. Inhibition of skin 5α-reductase by oral contraceptive progestins<i>in vitro</i> Gynecological Endocrinology · 2000 · 78 citations
    18. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    19. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    20. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    21. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations
    22. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    23. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 51 citations
    24. Is the metabolism of testosterone to 5α-dihydrotestosterone required for androgen action in the skin? British Journal of Dermatology · 1982 · 14 citations
    25. Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors Assay and Drug Development Technologies · 2018 · 11 citations
    26. Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility1 Biology of Reproduction · 2004 · 35 citations
    27. A Role for Steroid 5 alpha-reductase 1 in Vascular Remodelling During Endometrial Decidualisation bioRxiv (Cold Spring Harbor Laboratory) · 2022
    28. Novel inhibitors of 5α-reductase Expert Opinion on Therapeutic Patents · 2002 · 20 citations
    29. FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 17 citations
    30. Hormonal control of 5.ALPHA.-reductase activity in hamster sebaceous glands. Endocrinologia Japonica · 1982 · 4 citations