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The dutasteride nanoemulsion could improve hair loss treatment by enhancing drug penetration and retention in hair follicles.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Three siblings with a rare genetic condition had abnormal sexual development and chose different gender identities, needing surgery and therapy.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Compounds from the plant Mammea siamensis may help treat hair loss.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Chinese medicine may help treat hair loss by affecting genes and enzyme activity.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.