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Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Four-amino acid part makes enzyme sensitive to finasteride.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Taking both finasteride and dutasteride for prostate issues may raise the risk of heart problems.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

5α-reductase inhibitors help shrink the prostate, improve urinary symptoms, and may reduce prostate cancer risk.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Minoxidil may help treat hair loss by reducing the activity of a specific enzyme linked to baldness.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Dutasteride may help protect neurons and reduce inflammation in Parkinson's disease.

Dutasteride is more efficient than finasteride, but individual results vary.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.