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    Research 601–630 of 1000+

    1. GhDET2, a steroid 5α‐reductase, plays an important role in cotton fiber cell initiation and elongation The Plant Journal · 2007 · 193 citations
    2. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    3. A New Look at the 5?-Reductase Inhibitor Finasteride Cns Drug Reviews · 2006 · 137 citations
    4. Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production JAMA · 2012 · 124 citations
    5. Association of Suicidality and Depression With 5α-Reductase Inhibitors JAMA Internal Medicine · 2017 · 90 citations
    6. Inhibition of skin 5α-reductase by oral contraceptive progestins<i>in vitro</i> Gynecological Endocrinology · 2000 · 78 citations
    7. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 68 citations
    8. A Randomized, Double-Blind, Placebo-Controlled Trial to Determine the Effectiveness of Botanically Derived Inhibitors of 5-<i>α</i>-Reductase in the Treatment of Androgenetic Alopecia Journal of Alternative and Complementary Medicine · 2002 · 65 citations
    9. Effect of 5α-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials The Journal of Sexual Medicine · 2016 · 57 citations
    10. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats Brain Research · 2013 · 51 citations
    11. The effect of spironolactone on genital skin 5α-reductase activity 1985 · 50 citations
    12. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    13. Anabolic effects of testosterone are preserved during inhibition of 5α-reductase 2007 · 42 citations
    14. Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy 2011 · 39 citations
    15. Five-alpha-reductase Inhibitors for prostate cancer prevention. The Cochrane library · 2008 · 37 citations
    16. 7 Regulation of androgen receptor and 5α-reductase in the skin of normal and hirsute women Clinics in endocrinology and metabolism · 1986 · 35 citations
    17. Long-term Oral Administration of 5α-reductase Inhibitor Attenuates Erectile Function by Inhibiting Autophagy and Promoting Apoptosis of Smooth Muscle Cells in Corpus Cavernosum of Aged Rats Urology · 2013 · 34 citations
    18. <i>Curcuma aeruginosa</i>, a novel botanically derived 5α-reductase inhibitor in the treatment of male-pattern baldness: a multicenter, randomized, double-blind, placebo-controlled study Journal of Dermatological Treatment · 2011 · 34 citations
    19. Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens Andrologia · 2013 · 33 citations
    20. Male Breast Cancer and 5α-Reductase Inhibitors Finasteride and Dutasteride The Journal of Urology · 2013 · 32 citations
    21. Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase BJU international · 2009 · 29 citations
    22. Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles Archives of Dermatological Research · 1999 · 28 citations
    23. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    24. Long-term use of 5α-reductase inhibitors and the risk of male breast cancer Cancer Causes & Control · 2014 · 28 citations
    25. Benzo[<i>c</i>]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 Journal of Medicinal Chemistry · 2000 · 28 citations
    26. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    27. Different patterns of 5α-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells Biochemical and Biophysical Research Communications · 2008 · 22 citations
    28. Bladder Cancer Survival of Men Receiving 5α-Reductase Inhibitors The Journal of Urology · 2018 · 20 citations
    29. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    30. Development of a new gas chromatography–mass spectrometry (GC–MS) methodology for the evaluation of 5α-reductase activity Talanta · 2013 · 17 citations