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Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

The herbal hair cream could help treat male pattern baldness by blocking a baldness-related enzyme and might be worth further investigation.

Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.

Finasteride reduces new brain cells in male mice, possibly causing depression.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.

Red pigmented rice, like Sang-Yod rice, could help promote hair growth and prevent hair loss.

Equisetum debile extracts may help with skin whitening, anti-wrinkle, and anti-hair loss treatments.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.

Padina arborescens and its component MOGG may help prevent hair loss through several actions, including blocking a hair loss-related enzyme.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

Cynomorium songaricum has many health benefits and could help with hair regrowth.

Peanut callus extract helps grow hair and prevent hair loss.

Extracts improve hair growth in alopecia.

Male hormones can decrease the ability of immune cells to fight bacteria.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

4-(4-Phenoxybenzoyl)benzoic acid derivatives can both increase and decrease certain types of reactive oxygen species, and may be relevant to hair loss.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride and minoxidil together promote hair growth better than either alone.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.