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    Research 751–780 of 1000+

    1. Key targets of hormonal treatment of prostate cancer. Part 2: the androgen receptor and 5α-reductase BJU international · 2009 · 29 citations
    2. Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles Archives of Dermatological Research · 1999 · 28 citations
    3. Benzo[<i>c</i>]quinolizin-3-ones: A Novel Class of Potent and Selective Nonsteroidal Inhibitors of Human Steroid 5α-Reductase 1 Journal of Medicinal Chemistry · 2000 · 28 citations
    4. 12 Treatment of hirsutism with 5α-reductase inhibitors Clinics in endocrinology and metabolism · 1986 · 28 citations
    5. The Neurosteroidogenic Enzyme 5α-Reductase Mediates Psychotic-Like Complications of Sleep Deprivation Neuropsychopharmacology · 2017 · 27 citations
    6. Novel Lead Generation through Hypothetical Pharmacophore Three-Dimensional Database Searching: Discovery of Isoflavonoids as Nonsteroidal Inhibitors of Rat 5α-Reductase Journal of Medicinal Chemistry · 2001 · 27 citations
    7. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations
    8. Different patterns of 5α-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells Biochemical and Biophysical Research Communications · 2008 · 22 citations
    9. Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase Tetrahedron Letters · 1995 · 20 citations
    10. Novel 5α-Reductase Inhibitors:  Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids Journal of Medicinal Chemistry · 2005 · 18 citations
    11. Geranylated Coumarins From Thai Medicinal Plant Mammea siamensis With Testosterone 5α-Reductase Inhibitory Activity Frontiers in Chemistry · 2020 · 17 citations
    12. Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors Bioorganic & Medicinal Chemistry · 2015 · 17 citations
    13. Development of a new gas chromatography–mass spectrometry (GC–MS) methodology for the evaluation of 5α-reductase activity Talanta · 2013 · 17 citations
    14. Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach European journal of medicinal chemistry · 2012 · 17 citations
    15. The new paradigm for androgenetic alopecia and plant-based folk remedies: 5α-reductase inhibition, reversal of secondary microinflammation and improving insulin resistance Journal of Ethnopharmacology · 2018 · 16 citations
    16. Novel C-6 substituted and unsubstituted pregnane derivatives as 5α-reductase inhibitors and their effect on hamster flank organs diameter size Steroids · 2009 · 15 citations
    17. Synthesis and 5α-reductase inhibitory activity of 8-substituted benzo[ƒ]quinolinones derived from palladium mediated coupling reactions Bioorganic & Medicinal Chemistry Letters · 1998 · 14 citations
    18. Steroid 5α-reductase 2 deficiency leads to reduced dominance-related and impulse-control behaviors Psychoneuroendocrinology · 2018 · 14 citations
    19. New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors Steroids · 2011 · 14 citations
    20. Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin The Journal of Clinical Endocrinology & Metabolism · 1998 · 13 citations
    21. The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men’s Health Current Urology Reports · 2018 · 13 citations
    22. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors Chemical & Pharmaceutical Bulletin · 2017 · 13 citations
    23. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids Steroids · 2015 · 13 citations
    24. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
    25. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    26. Uromedic&#174; Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor &lt;em&gt;in Vitro&lt;/em&gt; Pharmacology & pharmacy · 2018 · 12 citations
    27. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    28. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    29. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    30. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations