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A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Finasteride reduces AML cell growth by inhibiting androgen receptors.

Dutasteride is more effective than finasteride for treating BPH without extra safety risks.

Finasteride does not negatively affect male reproductive function.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

Higher doses of 5α-reductase inhibitors reduce mortality risk, while lower doses increase suicide risk.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

The conclusion is that doctors should be careful when prescribing 5α-reductase inhibitors due to possible serious side effects, and they should discuss these risks with patients.

Liposomes are not better than acetone for applying DHT on skin.

Garden cress extract may help treat skin inflammation and androgen-related disorders.

The document corrects an author's affiliation in previous articles about COVID-19 and its links to hair loss and hormones.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.