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Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Unripe fruits of three banana species have many health-boosting compounds useful for medicine.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

New pregnane derivatives are effective at inhibiting an enzyme linked to hair loss and reducing oil gland activity.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Compound 15a was effective in inhibiting 5α-reductase.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Four-amino acid part makes enzyme sensitive to finasteride.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Certain Dibenzo derivatives may help treat prostate cancer.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

New compounds may soon be tested to treat excessive hair growth in women.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

Finasteride helps treat hair loss by blocking enzyme activity.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.