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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Men with male pattern baldness may not have different hormone levels, but their hair follicles are likely more sensitive to hormones.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

People with hair loss have different hormone levels, and these hormones can affect hair growth.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.

Hormones and neuropeptides affect hair growth, with androgens having opposite effects on beard and scalp hair.

Ultra-high molecular weight poly-γ-glutamic acid may help promote hair growth.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Oleanolic acid improved hair growth in mice by affecting hair growth pathways and reducing inflammation.

Male pattern hair loss may be linked to the developmental origins of hair follicles.

Saw Palmetto is a safe and effective natural remedy for treating benign prostatic hyperplasia (BPH).

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

Testosterone in human pancreas cells boosts insulin production.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.

Finasteride and dutasteride can cause sexual problems like impotence and low libido.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Androgen treatment with dihydrotestosterone may help maintain height in patients with 5-α-reductase type 2 deficiency, especially before puberty.

High levels of 3 alpha-diol glucuronide in the blood are a marker of increased androgen action in women with excessive hair growth of unknown cause.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.