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MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Personalized treatments for hair loss are becoming more effective by using genetic information.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Finasteride potentially treats hair loss by reducing DHT production.

Finasteride helps treat hair loss by blocking enzyme activity.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Suppressing certain hormones might help prevent prostate cancer.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Extracts improve hair growth in alopecia.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Finasteride negatively affects fish reproduction and gonadal development.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Finasteride improves hair growth in men with androgenetic alopecia.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.