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Flutamide improves female hair loss when other treatments fail, but may cause liver toxicity.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

The document explains hair biology, the causes of hair loss, and reviews various hair loss treatments.

PCOS is a common hormonal disorder in women, treated with lifestyle changes, medication, and patient education.

Korean hair is typically thicker with a slower growth rate, and treatments like Dutasteride are effective for male pattern hair loss without major side effects.

Testosterone increases fluid secretion and aquaporin expression in the vas deferens, which is important for male fertility.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride reduces hair growth and is safe for women with excessive hair.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Finasteride doesn't affect hormone levels in normal men.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

5-alpha-reductase inhibitors may help stabilize or slow down hair loss in some frontal fibrosing alopecia patients, but more research is needed to confirm their effectiveness and safety.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.

No link found between specific genes and female pattern hair loss.

Finasteride reduces movement issues in Parkinson's disease rats.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.