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    Research 91–120 of 1000+

    1. Early embryonic exposure of freshwater gastropods to pharmaceutical 5-alpha-reductase inhibitors results in a surprising open-coiled “banana-shaped” shell Scientific reports · 2019 · 13 citations
    2. The Impact of 5α-Reductase Inhibitor Use for Male Pattern Hair Loss on Men’s Health Current Urology Reports · 2018 · 13 citations
    3. Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors Chemical & Pharmaceutical Bulletin · 2017 · 13 citations
    4. Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids Steroids · 2015 · 13 citations
    5. Inhibitors of 5α-reductase-related side effects in patients seeking medical care for sexual dysfunction. PubMed · 2012 · 13 citations
    6. 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1 Bioorganic & medicinal chemistry letters · 2007 · 13 citations
    7. Synthesis and Pharmacological Evaluation of New Progesterone Esters as 5.ALPHA.-Reductase Inhibitors Chemical and Pharmaceutical Bulletin · 2005 · 13 citations
    8. Luteinizing Hormone and Human Chorionic Gonadotropin Decrease Type 2 5α-Reductase and Androgen Receptor Protein Levels in Women’s Skin The Journal of Clinical Endocrinology & Metabolism · 1998 · 13 citations
    9. Exploring the Inhibitory Potential of Phytosterols β-Sitosterol, Stigmasterol, and Campesterol on 5-Alpha Reductase Activity in the Human Prostate: An In Vitro and In Silico Approach Plants · 2024 · 12 citations
    10. May patients receiving 5-alpha-reductase inhibitors be in higher risk of COVID-19 complications? Medical hypotheses · 2020 · 12 citations
    11. Development and evaluation of antisense shRNA-encoding plasmid loaded solid lipid nanoparticles against 5-α reductase activity Journal of Drug Delivery Science and Technology · 2018 · 12 citations
    12. Uromedic® Pumpkin Seed Derived Δ7-Sterols, Extract and Oil Inhibit 5α-Reductases and Bind to Androgen Receptor <em>in Vitro</em> Pharmacology & pharmacy · 2018 · 12 citations
    13. Effect of C-ring modifications in benzo[c]quinolizin-3-ones, new selective inhibitors of human 5α-reductase 1 Bioorganic & Medicinal Chemistry · 2001 · 12 citations
    14. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    15. Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects Journal of the American Chemical Society · 1995 · 12 citations
    16. Impact of Alpha Blockers, 5-alpha Reductase Inhibitors and Combination Therapy on Sexual Function Current Urology Reports · 2014 · 11 citations
    17. Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients. 1996 · 11 citations
    18. Docking and Molecular Dynamics Identify Leads against 5 Alpha Reductase 2 for Benign Prostate Hyperplasia Treatment Journal of Chemistry · 2023 · 10 citations
    19. Sexual Problems of Men With Androgenic Alopecia Treated With 5-Alpha Reductase Inhibitors Sexual medicine reviews · 2018 · 10 citations
    20. Health Promotion Potential of Vegetables Cultivated in Northern Thailand: A Preliminary Screening of Tannin and Flavonoid Contents, 5α-Reductase Inhibition, Astringent Activity, and Antioxidant Activities Journal of Evidence-Based Complementary & Alternative Medicine · 2017 · 10 citations
    21. Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects Skin research and technology · 2014 · 10 citations
    22. Receipt of 5-Alpha Reductase Inhibitors Before Radical Cystectomy: Do They Render High-Grade Bladder Tumors Less Aggressive? Clinical genitourinary cancer · 2019 · 9 citations
    23. An Old Problem with a New Cause-5 Alpha Reductase Inhibitors and Persistent Sexual Dysfunction The Journal of Sexual Medicine · 2011 · 9 citations
    24. Synthesis and activity of 8-substituted benzo[c]quinolizin-3-ones as dual inhibitors of human 5α-reductases 1 and 2 Bioorganic & Medicinal Chemistry Letters · 2004 · 9 citations
    25. COMBINATION OF AN ANTIANDROGEN AND A 5α-REDUCTASE INHIBITOR: A FURTHER STEP TOWARDS TOTAL ANDROGEN BLOCKADE? Endocrinology · 1991 · 9 citations
    26. Phytochemicals With Anti 5-alpha-reductase Activity: A Prospective For Prostate Cancer Treatment F1000Research · 2021 · 8 citations
    27. Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2 Steroids · 2017 · 8 citations
    28. Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne Journal of Dermatology · 2010 · 8 citations
    29. Synthesis and Biological Evaluation of 4-(4-(Alkyl-and Phenylaminocarbonyl)benzoyl)benzoic Acid Derivatives as Non-steroidal Inhibitors of Steroid 5α-Reductase Isozymes 1 and 2 Archiv Der Pharmazie · 2002 · 8 citations
    30. Synthesis of Spiro[cyclohexane-1,2?-[2H]indene] derivatives as inhibitors of steroid 5?-reductase Helvetica Chimica Acta · 1995 · 8 citations