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    Research 451–480 of 1000+

    1. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    2. The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer 2008 · 108 citations
    3. Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp British Journal of Dermatology · 1999 · 100 citations
    4. Structure of human type II 5 alpha-reductase gene Endocrinology · 1992 · 76 citations
    5. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    6. The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men 2008 · 72 citations
    7. Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis International Journal of Andrology · 2017 · 66 citations
    8. Discovery and Clinical Development of Dutasteride, a Potent Dual 5α- Reductase Inhibitor Current topics in medicinal chemistry · 2006 · 58 citations
    9. Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study Steroids · 1998 · 56 citations
    10. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation Psychoneuroendocrinology · 2011 · 53 citations
    11. Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia Current pharmaceutical design · 2006 · 52 citations
    12. The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating Psychoneuroendocrinology · 2015 · 49 citations
    13. Actions of 5α-reductase inhibitors on the epididymis Molecular and Cellular Endocrinology · 2006 · 48 citations
    14. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations
    15. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice Psychoneuroendocrinology · 2012 · 42 citations
    16. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    17. Safety concerns regarding 5α reductase inhibitors for the treatment of androgenetic alopecia Current Opinion in Endocrinology, Diabetes and Obesity · 2015 · 33 citations
    18. Inhibition of 5α‐Reductase Activity in Late Pregnancy Decreases Gestational Length and Fecundity and Impairs Object Memory and Central Progestogen Milieu of Juvenile Rat Offspring Journal of Neuroendocrinology · 2011 · 32 citations
    19. The Effect of 5 -Reductase Inhibitors on Erectile Function International Journal of Andrology · 2008 · 31 citations
    20. The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase? Journal of neuroendocrinology · 2013 · 24 citations
    21. Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes <i>In Vitro</i> Hormone and metabolic research · 2007 · 24 citations
    22. Finasteride: The First 5α-Reductase Inhibitor Pharmacotherapy · 1993 · 23 citations
    23. Safety of 5α-reductase inhibitors and spironolactone in breast cancer patients receiving endocrine therapies Breast Cancer Research and Treatment · 2018 · 22 citations
    24. Inhibitors of 5α -Reductase Type I in LNCaP Cells from the Roots of Angelica koreana Planta Medica · 2002 · 22 citations
    25. Novel inhibitors of 5α-reductase Expert Opinion on Therapeutic Patents · 2002 · 20 citations
    26. FCE 28260, a new 5α-reductase inhibitor: In vitro and in vivo effects The Journal of Steroid Biochemistry and Molecular Biology · 1996 · 17 citations
    27. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    28. Enhanced skin permeation of 5α-reductase inhibitors entrapped into surface-modified liquid crystalline nanoparticles Archives of Pharmacal Research · 2014 · 16 citations
    29. Inhibition of 5α Reductase Impairs Cognitive Performance, Alters Dendritic Morphology and Increases Tau Phosphorylation in the Hippocampus of Male 3xTg-AD Mice Neuroscience · 2020 · 13 citations
    30. Is there a role for 5α‐reductase inhibitors in transgender individuals? International Journal of Andrology · 2020 · 10 citations