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Finasteride treatment changes Cx43 in rat testes, possibly causing fertility issues.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

New treatments for skin and hair repair show promise, but further improvements are needed.

Testosterone may slow down wound healing and increase inflammation.

New treatments for PCOS show promise, but no current medication treats all aspects of the condition.

Resveratrol helps prevent finasteride-induced damage in male rats, improving reproductive function.

Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Higher IGF-1 levels in hair follicles link to better finasteride results for hair loss.

Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.

Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.

About one-third of Saudi women with female pattern hair loss also have thinning hair at the back of their head.

Androgenetic alopecia is linked to heart disease, metabolic issues, and mental health problems.

The Chinese herbal supplement BeauTop can potentially boost hair growth and thickness by increasing a protein called Vascular Endothelial Growth Factor.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

Menopause can cause hair thinning and texture changes due to hormonal and metabolic shifts.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

Taohong Siwu Decoction may help treat hair loss by targeting multiple genes and pathways.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Some skin, hair, and nail supplements can be toxic, interact with medications, affect lab tests, and may increase cancer risk.

Origanum vulgare leaf extract reduces liver and kidney damage caused by finasteride in mice.

Certain ESR1 gene variations may affect hormone levels and fat distribution in women with high male hormone levels.

The rat model showed early perimenopause with regular cycles and low hormones, and late perimenopause with irregular cycles and higher hormone levels.