47 citations,
April 2003 in “Journal of dermatological science” Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.
55 citations,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
14 citations,
February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
January 2021 in “Journal of cosmetology & trichology” Ageratum conyzoides L. extract may effectively and safely treat hair loss.
15 citations,
April 2003 in “Journal of Dermatological Science” Gene differences may affect baldness treatment response in Korean men.
13 citations,
January 2019 in “Endocrine journal” Dihydrotestosterone treatment can help penis growth in boys with 5α-reductase deficiency but doesn't fully normalize size after puberty.
2 citations,
June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
6 citations,
April 2017 in “Frontiers in Pharmacology” Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
July 2023 in “International journal of research publications” Green coffee bean extract didn't grow hair but reduced a hair loss-related enzyme in rats.
March 2024 in “Cleveland Clinic journal of medicine” Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.
7 citations,
August 2006 in “Maturitas” Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.
20 citations,
January 2003 in “Chemical and Pharmaceutical Bulletin” The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
22 citations,
August 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
57 citations,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
June 2023 in “International journal of research in ayurveda and pharmacy” Dhatryadi Rasayana, an Ayurvedic herbal mix, may be a safe and effective way to prevent premature hair greying.
110 citations,
October 2019 in “Translational Andrology and Urology” More men are getting benign prostatic hyperplasia, and there are many treatments, from medication to surgery, with new methods being developed.
5 citations,
July 1994 in “PubMed” Finasteride, when taken daily, lowers dihydrotestosterone levels but doesn't noticeably affect adrenal steroid production, except by blocking the 5 alpha-reductase enzyme.
26 citations,
January 2002 in “Advances in experimental medicine and biology” Finasteride, originally for prostate issues, also treats hair loss, similar to effects from certain plants.
December 2022 in “Journal of applied biological chemistry” Betula platyphylla extract, particularly the H3-2 fraction, may help treat hair loss by promoting cell growth and inhibiting a hair loss-related enzyme.
17 citations,
October 2013 in “Plastic and reconstructive surgery. Global open” Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.
1 citations,
January 2018 in “Journal of Cosmetics, Dermatological Sciences and Applications” Ostrich antibodies helped regrow hair in men with hair loss, but the application needs to be easier.
6 citations,
October 2000 in “International Journal of Dermatology” Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.
November 2023 in “Clinical, Cosmetic and Investigational Dermatology” Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.
1 citations,
March 2021 in “Phytomedicine plus” Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
4 citations,
August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
24 citations,
March 2002 in “Expert opinion on investigational drugs” Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
59 citations,
March 2020 in “Journal of Biomedical Science” Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
67 citations,
July 2006 in “Clinics in Dermatology” Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.