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Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Compound 15a was effective in inhibiting 5α-reductase.

Solanum nigrum may help treat hair loss.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Finasteride reduces opioid use and withdrawal symptoms in animals.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

Finasteride may help reduce opioid use.

Certain drugs that block specific enzymes can help treat prostate diseases.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

Dutasteride may help shrink prostate cancer tumors.

Finasteride harms Daphnia magna's reproduction and metabolism.

Finasteride may help reduce anxiety and depression in elderly but might cause depression in young men.

Teak leaf extract contains compounds that could help treat hair loss.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Oral finasteride and dutasteride may negatively affect erectile function in rats.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Finasteride potentially treats hair loss by reducing DHT production.

5 alpha-reductase inhibitors like finasteride may lower prostate cancer risk and improve cancer screening.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.