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    Research 211–240 of 1000+

    1. Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study Life · 2023
    2. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    3. MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen<sup>1</sup> The Journal of Clinical Endocrinology & Metabolism · 1997 · 37 citations
    4. Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo Archives of Dermatological Research · 2021 · 18 citations
    5. Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor Bioorganic & Medicinal Chemistry Letters · 2010 · 18 citations
    6. Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche. Journal of Investigative Dermatology · 1998 · 10 citations
    7. Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction Mass spectrometry letters · 2012 · 8 citations
    8. Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 11 citations
    9. Finasteride, a 5alpha-reductase enzyme inhibitor, alone and synergism with a neurosteroid reduces responsiveness to nociceptive stimuli in male rat Journal of Pain · 2009
    10. Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions Journal of Functional Biomaterials · 2018 · 7 citations
    11. Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system DOAJ (DOAJ: Directory of Open Access Journals) · 2016 · 2 citations
    12. Administration Of 45% Robusta (Coffea canephora) Green Coffee Bean Ethanol Extract Solution Could Not Increased Hair Growth But Inhibited The Increase Of 5α-Reductase Type 1 Levels In Male Wistar Rats (Rattus norvegicus) Exposed To Topical Testosterone International journal of research publications · 2023
    13. Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors Estudo Geral (Universidade de Coimbra) · 2013
    14. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    15. Modulating testosterone pathway: a new strategy to tackle male skin aging? Clinical Interventions in Aging · 2012 · 6 citations
    16. 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish Communications Biology · 2026
    17. Steroidogenic Isoenzymes in Human Hair and Their Potential Role in Androgenetic Alopecia Dermatology · 2003 · 31 citations
    18. Attenzione divisa nei pazienti con cerebrolesione acquisita Journal of Medicinal Chemistry · 2008
    19. In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands Current Enzyme Inhibition · 2020
    20. Simultaneous Target-Mediated Drug Disposition-Pharmacodynamic (TMDD-PD) Modeling of Finasteride and Dutasteride: Impact of Target Binding and Turnover on Non-linear Pharmacokinetics The AAPS Journal · 2025
    21. Identification of bioactive compounds from thai plant extracts with hair growth promoting activity on human hair dermal papilla cells 2013
    22. 5α-Reductases In Human Physiology: an Unfolding Story Endocrine Practice · 2012 · 44 citations
    23. Molecular Interactions of New Pregnenedione Derivatives Chemical and Pharmaceutical Bulletin · 2003 · 20 citations
    24. Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Punica granatum Peel as a Potential Anti-Alopecia Treatment EAS Journal of Pharmacy and Pharmacology · 2024
    25. Decoding Pumpkin Seeds for Hair Loss: A Computational Perspective Zenodo (CERN European Organization for Nuclear Research) · 2023
    26. Species Differences in Prostatic Steroid 5<i>α</i>-Reductases of Rat, Dog, and Human Endocrinology · 1985 · 193 citations
    27. Bioactive metabolites of edible mushrooms efficacious against androgenic alopecia: Targeting SRD5A2 using computational approach Research Square (Research Square) · 2022
    28. Urinary symptoms in patients with androgenetic alopecia Journal of The American Academy of Dermatology · 2010
    29. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary–adrenal axis response to restraint stress in adult male rats Brain Research · 2013 · 51 citations
    30. An overview of herbal alternatives in androgenetic alopecia Journal of Cosmetic Dermatology · 2019 · 26 citations