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The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Some herbs show promise as antiandrogenic agents.

Finasteride doesn't affect erections much, but may decrease libido in men.

Finasteride is not expected to be effective for treating Acne vulgaris.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Finasteride helps protect brain in old male rats.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Oral ivermectin effectively cured scabies with minimal side effects, and finasteride promoted hair growth in men with hair loss.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Finasteride doesn't affect sleep spindles in men.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Finasteride and minoxidil are effective for hair loss, but continued research is needed for better treatments.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Finasteride increases hair count in middle-aged and elderly men without causing sexual dysfunction.

Hair loss treated with minoxidil, finasteride, laser/light, hair transplant, and scalp prostheses; more research needed for skin of color.

The herbal extract was found to effectively reduce and prevent hair loss without any side effects.