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    Research 571–600 of 1000+

    1. Physcion, a novel inhibitor of 5α-reductase that promotes hair growth in vitro and in vivo Archives of Dermatological Research · 2021 · 18 citations
    2. Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes Heliyon · 2024 · 6 citations
    3. 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism Neurochemistry International · 2026
    4. Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses Journal of Biological Chemistry · 2008 · 27 citations
    5. Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study BMJ. British medical journal · 2019 · 29 citations
    6. Effect of a novel steroid (PM-9) on the inhibition of 5α-reductase present in Penicillium crustosum broths Steroids · 2003 · 22 citations
    7. Finasteride: a 5 alpha-reductase inhibitor. PubMed · 1993 · 12 citations
    8. The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder Journal of Clinical Investigation · 2021 · 8 citations
    9. Prefrontal 5α-reductase 2 mediates male-specific acute stress response Science Advances · 2025 · 5 citations
    10. Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition Plants · 2023 · 1 citations
    11. Role of 5α-reductase inhibitors in androgen-stimulated skin disorders. PubMed · 2013 · 3 citations
    12. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    13. Intracrine and Myotrophic Roles of 5α-Reductase and Androgens Medicine and science in sports and exercise · 2011 · 35 citations
    14. Minoxidil Acts as an Antiandrogen: A Study of 5α-reductase Type 2 Gene Expression in a Human Keratinocyte Cell Line. PubMed · 2017 · 4 citations
    15. Fetal alpha 5-reductase Val89Leu mutation is associated with late miscarriage Reproductive biomedicine online · 2017 · 3 citations
    16. In silico structural prediction of human steroid 5α-reductase type II Medicinal Chemistry Research · 2016 · 3 citations
    17. The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles. PubMed · 2000 · 3 citations
    18. Anti-androgenetic effect of diphlorethohydroxycarmalol on testosterone-induced hair loss by inhibiting 5α-reductase and promoting Wnt/β-catenin signaling pathway in human dermal papilla cells Toxicology in Vitro · 2025 · 1 citations
    19. RE: EFFECT OF THE DUAL 5α-REDUCTASE INHIBITOR DUTASTERIDE ON MARKERS OF TUMOR REGRESSION IN PROSTATE CANCER 2005
    20. The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer 2008 · 108 citations
    21. The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men 2008 · 72 citations
    22. Isolation rearing-induced reduction of brain 5α-reductase expression: Relevance to dopaminergic impairments Neuropharmacology · 2011 · 48 citations
    23. Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice Psychoneuroendocrinology · 2012 · 42 citations
    24. Effect of thioredoxin reductase 1 on glucocorticoid receptor activity in human outer root sheath cells Biochemical and Biophysical Research Communications · 2007 · 34 citations
    25. The Implication of Neuroactive Steroids in Tourette's Syndrome Pathogenesis: A Role for 5α‐Reductase? Journal of neuroendocrinology · 2013 · 24 citations
    26. 17-Oximino-5-androsten-3β-yl esters: synthesis, antiproliferative activity, acute toxicity, and effect on serum androgen level Medicinal Chemistry Research · 2010 · 7 citations
    27. The Benefits of Dual Inhibition of 5α Reductase European Urology Supplements · 2006 · 4 citations
    28. Virtual Insights into Natural Compounds as Potential 5α-Reductase Type II Inhibitors: A Structure-Based Screening and Molecular Dynamics Simulation Study Life · 2023
    29. Dual effects of 5α-reductase inhibitor dutasteride on androgenetic alopecia and acne vulgaris Dermatologica Sinica · 2019
    30. Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor 2004 · 408 citations