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Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Finasteride effectively treats male hair loss, improving growth and density.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

New hybrid compound found to effectively prevent hair loss.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.

Starting 5-alpha reductase inhibitors does not significantly increase the risk of rhabdomyolysis in older men, but is linked to a higher risk of muscle conditions.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

Taking 5-alpha reductase inhibitors does not increase breast cancer risk in men.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

A man's low testosterone and related symptoms improved after he stopped taking hair loss drugs.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Dutasteride may help shrink prostate cancer tumors.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Cimicifuga racemosa extract may help prevent and treat prostate issues by inhibiting 5α-reductase.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.