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    Research 631–660 of 1000+

    1. Optimization and Characterization of TSG-Enriched Polygonum multiflorum Extract and Its Dual Mechanism Against Androgenetic Alopecia via 5α-Reductase Inhibition and Wnt/β-Catenin Activation International Journal of Molecular Sciences · 2026
    2. Therapeutic effect of <i>Nepenthes kampotiana</i> Lecomte ethanol extract (Nk-EE) on androgenic alopecia through the inhibition of apoptosis and 5α-reductase activity Natural Product Research · 2024
    3. Evaluation of Therapeutic Potential of a Selective 5α-reductase Inhibitor against Glioblastoma: Molecular Docking and In Vitro Insights Cell Biochemistry and Biophysics · 2025 · 1 citations
    4. Re: Association of Treatment with 5α-Reductase Inhibitors with Time to Diagnosis and Mortality in Prostate Cancer The Journal of Urology · 2019
    5. Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors Estudo Geral (Universidade de Coimbra) · 2013
    6. Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism The Journal of Clinical Endocrinology and Metabolism · 1994 · 17 citations
    7. Review of the Efficacy of Topical 5-Alpha Reductase Inhibitors for the Treatment of Androgenetic Alopecia Journal of Drugs in Dermatology · 2026
    8. Efficacy and safety of α-blockers plus 5α-reductase inhibitors for benign prostatic hyperplasia: a systematic review and meta-analysis European journal of medical research · 2026
    9. Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men The Journal of Clinical Endocrinology and Metabolism · 1992 · 9 citations
    10. Glioblastoma cells express crucial enzymes involved in androgen synthesis: 3β‐hydroxysteroid dehydrogenase, 17‐20α‐hydroxylase, 17β‐hydroxysteroid dehydrogenase and 5α‐reductase Endocrinology, diabetes & metabolism · 2021 · 5 citations
    11. Progesterone Promotes Anti-Anxiety/Depressant-like Behavior and Trophic Actions of BDNF in the Hippocampus of Female Nuclear Progesterone Receptor, but Not 5α-Reductase, Knockout Mice International Journal of Molecular Sciences · 2025 · 4 citations
    12. Reduced Prostate Cancer Risk in Patients with Androgenetic Alopecia Using 5-Alpha Reductase Inhibitors: A TriNetX Real-World Cohort Study Journal of the American Academy of Dermatology · 2026
    13. Benign Prostatic Hyperplasia Pharmacotherapy and Incident Ocular Surface Disease: Comparative Risk of Alpha-Blockers vs 5-Alpha Reductase Inhibitors Urology · 2026
    14. Association of breast cancer in men with exposure to 5-α reductase inhibitors: A RADAR report. Journal of Clinical Oncology · 2012
    15. 4‐MAPC, a 5α‐Reductase Inhibitor, Reduces Rat Ventral Prostate Weight, DNA, and Prostatein Concentrations Journal of Andrology · 1991 · 7 citations
    16. Ligand Based 3D-QSAR Study on a Series of Steroidal Human 5&#945;-Reductase Inhibitors Letters in Drug Design & Discovery · 2010 · 3 citations
    17. The Long-Term Effect Of Specific Type II 5??-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial The Journal of Urology · 2002 · 1 citations
    18. Psychiatric Comorbidity Related to the Therapy of Male Androgenetic Alopecia Independent of the 5–Alpha Reductase Pathway Skin appendage disorders · 2021
    19. Risk of estrogen-driven malignancies in females on 5-alpha reductase inhibitors Archives of Dermatological Research · 2024 · 1 citations
    20. Quality-of-life changes in women with female androgenetic alopecia treated with a methylsulfonylmethane-containing 5-alpha-reductase inhibitor: a clinical practice study Actas Dermo-Sifiliográficas · 2026
    21. Synthesis, Biological Evaluation and in silico Studies of Novel 5α-aza-Bhomo-3,5-secosteroids as Potential 5-reductase Inhibitors Letters in Drug Design & Discovery · 2016
    22. Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men The Journal of Clinical Endocrinology and Metabolism · 1996 · 7 citations
    23. The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness The Journal of Clinical Endocrinology and Metabolism · 1994 · 61 citations
    24. Fully automated chip-based nanoelectrospray ionization-mass spectrometry as an effective tool for rapid and high-throughput screening of 5α-reductase inhibitors Analytical and Bioanalytical Chemistry · 2020 · 7 citations
    25. 5α‐Reductase Isozymes and Androgen Actions in the Prostate Annals of the New York Academy of Sciences · 2009 · 93 citations
    26. The 5alpha-reductase type 1, but not type 2, gene is expressed in anagen hairs plucked from the vertex area of the scalp of hirsute women and normal individuals Brazilian Journal of Medical and Biological Research · 2003 · 17 citations
    27. 5α-Reductase, an enzyme regulating glucocorticoid action in the testis of Rhinella arenarum (Amphibia: Anura) General and Comparative Endocrinology · 2012 · 8 citations
    28. 5α-Reductases In Human Physiology: an Unfolding Story Endocrine Practice · 2012 · 44 citations
    29. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    30. 5α-Reductase underscores the development of pectoral fin breeding tubercles in zebrafish Communications Biology · 2026