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    Research 541–570 of 1000+

    1. Clinical dose ranging studies with finasteride, a type 2 5α-reductase inhibitor, in men with male pattern hair loss Journal of The American Academy of Dermatology · 1999 · 46 citations
    2. Human type 3 5α-reductase is expressed in peripheral tissues at higher levels than types 1 and 2 and its activity is potently inhibited by finasteride and dutasteride Hormone Molecular Biology and Clinical Investigation · 2010 · 45 citations
    3. Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite Therapeutic Drug Monitoring · 2007 · 39 citations
    4. Leydig Cell Hyperplasia and Adenomas in Mice Treated with Finasteride, a 5α-Reductase Inhibitor: A Possible Mechanism Fundamental and applied toxicology · 1994 · 35 citations
    5. Finasteride: the first 5 alpha-reductase inhibitor. PubMed · 1993 · 34 citations
    6. Finasteride, a Type 2 5α-reductase inhibitor, in the treatment of men with androgenetic alopecia Expert Opinion on Investigational Drugs · 1999 · 32 citations
    7. Age-related changes in brain and pituitary 5α-reductase with finasteride (Proscar) treatment Neurobiology of Aging · 1995 · 26 citations
    8. Torilin from<i>Torilis japonica,</i>as a New Inhibitor of Testosterone 5α-Reductase Planta Medica · 2003 · 22 citations
    9. Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2015 · 21 citations
    10. Bee Venom Promotes Hair Growth in Association with Inhibiting 5α-Reductase Expression Biological & Pharmaceutical Bulletin · 2016 · 15 citations
    11. In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole Drug Metabolism and Disposition · 2011 · 14 citations
    12. Plasma androsterone/epiandrosterone sulfates as markers of 5α-reductase activity: Effect of finasteride in normal men Steroids · 1997 · 13 citations
    13. Establishment of type II 5α-reductase over-expressing cell line as an inhibitor screening model 2007 · 12 citations
    14. Inhibitory Effects of Serenoa repens on the Kinetic of Pig Prostatic Microsomal 5α-Reductase Activity Endocrine journal · 1998 · 12 citations
    15. Finasteride: a 5 alpha-reductase inhibitor. PubMed · 1993 · 12 citations
    16. Metabolic dysfunction in female mice with disruption of 5α-reductase 1 2017 · 11 citations
    17. The Long-Term Effect Of Specific Type II 5α-Reductase Inhibition With Finasteride on Bone Mineral Density in Men: Results of a 4-Year Placebo Controlled Trial The Journal of Urology · 2002 · 11 citations
    18. Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase The Journal of Steroid Biochemistry and Molecular Biology · 2000 · 11 citations
    19. Greater conversion of testosterone to 5α-dihydrotestosterone, reflecting increased peripheral 5α-reductase activity in nude mice treated with high doses of cyclosporine A Journal of Steroid Biochemistry · 1990 · 10 citations
    20. Comparative GC-MS Based In vitro Assays of 5α-Reductase Activity Using Rat Liver S9 Fraction Mass spectrometry letters · 2012 · 8 citations
    21. 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency European Urology · 1991 · 8 citations
    22. Interconnected PolymerS TeChnology (IPSTiC): An Effective Approach for the Modulation of 5α-Reductase Activity in Hair Loss Conditions Journal of Functional Biomaterials · 2018 · 7 citations
    23. Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men. The Journal of Clinical Endocrinology and Metabolism · 1996 · 6 citations
    24. Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase Bioorganic & Medicinal Chemistry · 1997 · 5 citations
    25. Hormonal control of 5.ALPHA.-reductase activity in hamster sebaceous glands. Endocrinologia Japonica · 1982 · 4 citations
    26. The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids Hormone Molecular Biology and Clinical Investigation · 2009 · 2 citations
    27. Improvement of Tissue Survival of Skin Flaps by 5α-Reductase Inhibitors: Possible Involvement of Nitric Oxide and Inducible Nitric Oxide Synthase PubMed · 2015 · 1 citations
    28. 0192 Estrogenic effects of 5-alpha-reductase inhibitors in male androgenetic alopecia patients Journal of Investigative Dermatology · 2025
    29. Concomitant immobilization of androgen receptors and 5α- reductase in androgenic alopecia International Journal of Dermatology Research · 2025
    30. Intraoperative Iris Behavior during Phacoemulsification Maneuvers in Rabbits Treated with Selective α1-Blocker, 5α-Reductase Inhibitor, or Anxiolytic Medication Journal of Personalized Medicine · 2024