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    Research 361–390 of 1000+

    1. Synthesis and Evaluation of 2‘-Substituted 4-(4‘-Carboxy- or 4‘-carboxymethylbenzylidene)-<i>N</i>-acylpiperidines: Highly Potent and in Vivo Active Steroid 5α-Reductase Type 2 Inhibitors Journal of Medicinal Chemistry · 2002 · 22 citations
    2. Inhibitory activities of Puerariae Flos against testosterone 5α-reductase and its hair growth promotion activities Journal of Natural Medicines · 2011 · 34 citations
    3. Steroid 5α-Reductase as a Novel Therapeutic Target for Schizophrenia and Other Neuropsychiatric Disorders Current Pharmaceutical Design · 2011 · 72 citations
    4. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 51 citations
    5. Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum) I. Active Constituents Inhibiting Testosterone 5.ALPHA.-Reductase. Biological & Pharmaceutical Bulletin · 2002 · 38 citations
    6. Recent Advances in the Chemistry and Pharmacological Activity of New Steroidal Antiandrogens and 5α-Reductase Inhibitors Current Medicinal Chemistry · 2005 · 20 citations
    7. Symptoms of hypogonadism caused by 5α-reductase inhibitors International journal of family & community medicine · 2017
    8. Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010 · 223 citations
    9. Structure of human steroid 5α-reductase 2 with the anti-androgen drug finasteride Nature Communications · 2020 · 30 citations
    10. Is there a role for 5α‐reductase inhibitors in transgender individuals? International Journal of Andrology · 2020 · 10 citations
    11. Evolution, classification, structure, and functional diversification of steroid 5α-reductase family in eukaryotes Heliyon · 2024 · 6 citations
    12. Prefrontal 5α-reductase 2 mediates male-specific acute stress response Science Advances · 2025 · 5 citations
    13. Structure of human steroid 5α-reductase 2 with anti-androgen drug finasteride Research Square (Research Square) · 2020 · 4 citations
    14. Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition Plants · 2023 · 1 citations
    15. In Silico Screening of DrugBank Compounds as Potential Inhibitors for Human Steroid 5α-Reductase 2 for Androgen-Related Diseases Biointerface Research in Applied Chemistry · 2023
    16. Analysis of genetic polymorphisms of steroid 5α-reductase type 1 and 2 genes in Korean men with androgenetic alopecia Journal of Dermatological Science · 2003 · 15 citations
    17. Finasteride-Induced Inhibition of 5α-Reductase Type 2 Could Lead to Kidney Damage—Animal, Experimental Study International Journal of Environmental Research and Public Health · 2019 · 10 citations
    18. 1640: Polymorphisms in the 5α-Reductase Type 2 Gene and Response to Finasteride Treatment in BPH The Journal of Urology · 2006
    19. The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride Journal of The American Academy of Dermatology · 2006 · 215 citations
    20. Testosterone 5.ALPHA.-Reductase Inhibitory Active Constituents of Piper nigrum Leaf Biological & pharmaceutical bulletin · 2007 · 44 citations
    21. Steroid 5&#945;-Reductase Inhibitors Mini-reviews in Medicinal Chemistry · 2003 · 42 citations
    22. The Aromatase Inhibitor Fadrozole and the 5-Reductase Inhibitor Finasteride Affect Gonadal Differentiation and Gene Expression in the Frog <i>Silurana tropicalis</i> Sexual Development · 2009 · 37 citations
    23. Inhibition of 5α-Reductase Activity in SZ95 Sebocytes and HaCaT Keratinocytes <i>In Vitro</i> Hormone and metabolic research · 2007 · 24 citations
    24. A Review on Steroidal 5&#945;-Reductase Inhibitors for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2011 · 17 citations
    25. Effect of the 5α-reductase enzyme inhibitor dutasteride in the brain of intact and parkinsonian mice 2017 · 16 citations
    26. Saturable Binding of Finasteride to Steroid 5α-reductase as Determinant of Nonlinear Pharmacokinetics Drug Metabolism and Pharmacokinetics · 2010 · 16 citations
    27. Determination Method for Steroid 5α-Reductase Activity Using Liquid Chromatography/Atmospheric Pressure Chemical Ionization–Mass Spectrometry Analytical Sciences · 2005 · 13 citations
    28. Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors Medicinal Chemistry Research · 2017 · 12 citations
    29. Role of 5α-reductase inhibitors in androgen-stimulated skin disorders. PubMed · 2013 · 3 citations
    30. Re: Risk of Erectile Dysfunction Associated with Use of 5α-Reductase Inhibitors for Benign Prostatic Hyperplasia or Alopecia: Population Based Studies Using the Clinical Practice Research Datalink European Urology · 2017 · 2 citations