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    Research 721–750 of 1000+

    1. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997 · 416 citations
    2. Adverse Side Effects of 5α‐Reductase Inhibitors Therapy: Persistent Diminished Libido and Erectile Dysfunction and Depression in a Subset of Patients The Journal of Sexual Medicine · 2010 · 223 citations
    3. An overview on 5α-reductase inhibitors Steroids · 2009 · 219 citations
    4. The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss: Results of a randomized placebo-controlled study of dutasteride versus finasteride Journal of The American Academy of Dermatology · 2006 · 215 citations
    5. The Effect of 5α-Reductase Inhibition with Dutasteride and Finasteride on Semen Parameters and Serum Hormones in Healthy Men The Journal of Clinical Endocrinology and Metabolism · 2007 · 195 citations
    6. Synthesis and 5α-Reductase Inhibitory Activity of C21 Steroids Having 1,4-diene or 4,6-diene 20-ones and 4-Azasteroid 20-Oximes Molecules · 2011 · 186 citations
    7. Comparison of finasteride (proscar®), a 5α reductase inhibitor, and various commercial plant extracts in in vitro and in vivo 5α reductase inhibition The Prostate · 1993 · 124 citations
    8. Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment Journal of The American Academy of Dermatology · 1999 · 115 citations
    9. Adverse effects of 5α-reductase inhibitors: What do we know, don’t know, and need to know? Reviews in Endocrine and Metabolic Disorders · 2015 · 111 citations
    10. The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer 2008 · 108 citations
    11. Immunohistochemical localization of types 1 and 2 5α-reductase in human scalp British Journal of Dermatology · 1999 · 100 citations
    12. Production of 5α-Reduced Neurosteroids Is Developmentally Regulated and Shapes GABA<sub>A</sub>Miniature IPSCs in Lamina II of the Spinal Cord Journal of Neuroscience · 2004 · 88 citations
    13. Efficacy of imiquimod 5% cream in the treatment of equine sarcoids: a pilot study Veterinary Dermatology · 2006 · 76 citations
    14. Structure of human type II 5 alpha-reductase gene Endocrinology · 1992 · 76 citations
    15. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    16. Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats Journal of Heredity · 2007 · 75 citations
    17. The Effect of 5α-Reductase Inhibition With Dutasteride and Finasteride on Bone Mineral Density, Serum Lipoproteins, Hemoglobin, Prostate Specific Antigen and Sexual Function in Healthy Young Men 2008 · 72 citations
    18. Sexual dysfunction in subjects treated with inhibitors of 5α-reductase for benign prostatic hyperplasia: a comprehensive review and meta-analysis International Journal of Andrology · 2017 · 66 citations
    19. Twice Weekly 5 mg Dexamethasone Oral Pulse in the Treatment of Extensive Alopecia Areata The Journal of Dermatology · 1999 · 65 citations
    20. Antipsychotic-Like Properties of 5-α-Reductase Inhibitors Neuropsychopharmacology · 2008 · 64 citations
    21. Discovery and Clinical Development of Dutasteride, a Potent Dual 5&#945;- Reductase Inhibitor Current topics in medicinal chemistry · 2006 · 58 citations
    22. Effect of 5α-Dihydrotestosterone and Testosterone on Apoptosis in Human Dermal Papilla Cells Skin Pharmacology and Physiology · 2006 · 58 citations
    23. Effects of the 5α-Reductase Inhibitor Finasteride on Serum Levels of Gonadal, Adrenal, and Hypophyseal Hormones and its Clinical Significance: A Prospective Clinical Study Steroids · 1998 · 56 citations
    24. Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation Psychoneuroendocrinology · 2011 · 53 citations
    25. Inhibitors of 5&#945;-Reductase in the Treatment of Benign Prostatic Hyperplasia Current pharmaceutical design · 2006 · 52 citations
    26. The neurosteroidogenic enzyme 5α-reductase modulates the role of D1 dopamine receptors in rat sensorimotor gating Psychoneuroendocrinology · 2015 · 49 citations
    27. Inhibition of 5α‐Reduced Steroid Biosynthesis Impedes Acquisition of Ethanol Drinking in Male C57BL/6J Mice Alcoholism Clinical and Experimental Research · 2008 · 49 citations
    28. Actions of 5α-reductase inhibitors on the epididymis Molecular and Cellular Endocrinology · 2006 · 48 citations
    29. Severe follicular hyperplasia and spontaneous papilloma formation in transgenic mice expressing theneu oncogene under the control of the bovine keratin 5 promoter Molecular Carcinogenesis · 1998 · 47 citations
    30. Clinical application of 5α-reductase inhibitors Journal of endocrinological investigation · 2001 · 46 citations