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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Treatments for melanin disorders exist, but more effective options needed.

A new gene, JMJD1C, may affect testosterone levels in men.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

SHBG may be a useful early indicator and treatment target for PCOS.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.

Artesunate is generally safe for severe malaria, but patients should be monitored for delayed anemia after treatment.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Hormonal treatments are effective for severe or persistent acne and should be used with other acne therapies, considering potential side effects.

Nano-sized plant-based chemicals could improve cervical cancer treatment by being more effective and causing fewer side effects than current methods.

Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.