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Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

5 alpha reductase inhibitors can cause sexual, cognitive, and muscle side effects, and may slightly increase aggressive cancer risk.

Ursolic acid can shrink the prostate and lower a hormone linked to prostate growth in rats.

Estradiol and castration reduced prostate cancer development in rats when applied at early stages, but were ineffective after cancer was established.

Treatment during development affects hormone balance and sexual behavior in male rats.

Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

Male hormones worsen kidney transplant damage, but blocking them helps.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Women with AGA have more androstenedione and dihydrotestosterone, less copper and zinc; copper imbalance affects AGA; treatment improves hormones and minerals.

DHT inhibition may increase spinal bone growth in ankylosing spondylitis.

Some plant-based products might treat hair loss with fewer side effects than current medications.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Different hair growth phases affect how follicles respond to X-rays, and hormones like testosterone and dihydrotestosterone play a key role in baldness; transplanted hair can grow on bald scalp areas.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Dutasteride reduces DHT more effectively than finasteride.

The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.

Finasteride may cause kidney damage.

Muscles can make their own androgens, which may help muscle growth.

Caffeine in Alpecin shampoo may help prolong hair root activity and reduce hair loss.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Male pattern baldness is mainly caused by a hormone called dihydrotestosterone (DHT), and drugs that can block this hormone might help prevent hair loss.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.