research Clinical Application of 5α-Reductase Inhibitors
5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
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research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research 5α-Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
research Effects of the Anti-Androgen Finasteride on 5-Alpha-Reductase Activity in Human Gingival Fibroblasts in Response to Minocycline
Finasteride helps treat hair loss by blocking enzyme activity.
research Inhibition of Skin 5α-Reductase by Oral Contraceptive Progestins In Vitro
Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
research Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice
Stauntonia hexaphylla extract can help treat hair loss by blocking certain hormones.
research Mechanistic Synergy of Hair Growth Promotion by the Avicennia Marina Extract and Its Active Constituent Avicequinone C in Dermal Papilla Cells Isolated From Androgenic Alopecia Patients
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research Hormonal Manipulation of Benign Prostatic Hyperplasia
Finasteride and dutasteride are equally effective and safe for treating benign prostatic hyperplasia.
research The New Paradigm for Androgenetic Alopecia and Plant-Based Folk Remedies: 5α-Reductase Inhibition, Reversal of Secondary Microinflammation, and Improving Insulin Resistance
Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.
research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride
Dutasteride more effective for hair growth, but has more side effects than finasteride.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research AKR1D1 Regulates Glucocorticoid Availability and Glucocorticoid Receptor Activation in Human Hepatoma Cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research Risk of Poor Glycemic Control in Tamsulosin Versus Finasteride Users with Type 2 Diabetes Mellitus
Tamsulosin and finasteride have similar effects on blood sugar control in men with type 2 diabetes.
research Polycystic Ovary Syndrome: Dermatological Approach
Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.
research Polycystic Ovary Syndrome: Challenges in Adolescence
Diagnosing and managing PCOS in teens is hard, but early diagnosis and lifestyle changes are key, and more research is needed for long-term health.
research Hair Restoration Surgery: Follicular Unit Grafting
Follicular unit grafting is a procedure used to treat hair loss, where small hair grafts are placed into the scalp, with future treatments likely to involve smaller incisions and cell-based therapies.
research Finasteride
Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
research Androgenetic Alopecia: Therapy Update
There are many treatments for common hair loss, but more trials are needed to decide which are best.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Management of Hirsutism
Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.
research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Innovative Use of Spironolactone as an Antiandrogen in the Treatment of Female Pattern Hair Loss
Spironolactone helps regrow hair in women with hair loss.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
Birth control pills help treat skin and hair growth problems linked to high male hormone levels.
research Hair Loss in Women: Comprehensive Overview and Treatment Options
Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.
research Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment
Various treatments exist for hair loss, but more research is needed for better options.
research Experimental and Early Investigational Drugs for Androgenetic Alopecia
New hair loss treatments may include topical medications, injections, and improved transplant methods.
research The Additive Value of Platelet-Rich Plasma to Topical Minoxidil in the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Combining PRP with Minoxidil improves hair density and thickness more than Minoxidil alone.