research Stem Cells Tightly Regulate Dead Cell Clearance to Maintain Tissue Fitness
Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
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research Review of the Effects of 17α-Estradiol in Humans: A Less Feminizing Estrogen with Neuroprotective Potential
17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
research Demethylation of ITGAV Accelerates Osteogenic Differentiation in a Blast-Induced Heterotopic Ossification In Vitro Cell Culture Model
Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.
research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research The Evaluation of IL-4 Intron 3 VNTR and TNF-α (rs1799964) Gene Polymorphisms in Egyptian Patients with Alopecia Areata: A Case-Control Study
These specific gene polymorphisms are not linked to Alopecia Areata in Egyptians.
research Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis
Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
research Causal Effects of Genetically Determined Metabolites on Androgenetic Alopecia: A Two-Sample Mendelian Randomization Analysis
Certain metabolites can either protect against or increase the risk of hair loss.
research Keratin Disorders: From Gene to Therapy
New treatments targeting specific genes show promise for treating keratin disorders.
research SFRP2/DPP4 and FMO1/LSP1 Define Major Fibroblast Populations in Human Skin
Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
research WNT10A Promotes an Invasive and Self-Renewing Phenotype in Esophageal Squamous Cell Carcinoma
WNT10A helps esophageal cancer cells spread and keep renewing themselves.
research Role of Vitamin D and Calcium Signaling in Epidermal Wound Healing
Vitamin D and calcium are important for quick and effective skin wound healing.
research Characterization of Type II Rickets Model Rats to Reveal Functions of Vitamin D and Vitamin D Receptor
The research showed that Vitamin D and its receptor are important for healthy bones and normal hair and skin in rats.
research Noyes-Whitney Dissolution Model-Based pH-Sensitive Slow Release of Paclitaxel from Human Hair-Derived Keratin Microparticle Carriers
Human hair-derived particles can effectively carry and release the cancer drug Paclitaxel in a pH-sensitive manner, potentially targeting cancer cells while sparing healthy ones.
research Knowledge and Beliefs About the Use and Abuse of Oral Contraceptive Pills Among Males: A Mixed-Method Explanatory Sequential Study in Community Pharmacy Settings
Many men misuse oral contraceptive pills for things like hair growth and muscle gain.
research A Comparative Study of Materials Assembled from Recombinant K31 and K81 and Extracted Human Hair Keratins
Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
research Proteins in Scalp Hair of Preschool Children
Hair proteins in preschool children and their mothers could indicate developmental changes and health status.
research Minoxidil: Effectiveness and Prospects for Use in the Treatment of Androgenetic Alopecia
Minoxidil is an effective and safe treatment for common hair loss when applied to the skin, but more research is needed for optimal use.
research Enzymatic Synthesis of Alpha-Glucosyl-Baicalin Through Transglucosylation via Cyclodextrin Glucanotransferase in Water
Enzymatic synthesis improved the water solubility of the flavonoid baicalin, which may help treat hair loss conditions.
research Transport of Biotin in Human Keratinocytes
Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
research Transcriptome Meta-Analysis Confirms the Hidradenitis Suppurativa Pathogenic Triad: Upregulated Inflammation, Altered Epithelial Organization, and Dysregulated Metabolic Signaling
The research confirms that Hidradenitis Suppurativa is characterized by increased inflammation, disrupted skin cell organization, and abnormal metabolic processes.
research Genetics of Hidradenitis Suppurativa
Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.
research Effects of Dihydrotestosterone on Osteoblast Activity in Curdlan-Administered SKG Mice and Osteoprogenitor Cells in Patients with Ankylosing Spondylitis
DHT inhibition may increase spinal bone growth in ankylosing spondylitis.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Comparative Genome Analyses Reveal the Unique Genetic Composition and Selection Signals Underlying the Phenotypic Characteristics of Three Chinese Domestic Goat Breeds
Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.
research Hair Cortisol in Sheltered Cows and Its Association with Other Welfare Indicators
High hair cortisol levels indicate stress in cows due to poor shelter conditions and health issues.
research Bleached Hair as a Standard Template to Evaluate the Performance of Commercial Hair Repair Products
K18® and Olaplex® both effectively repair bleached hair, improving its strength, smoothness, and overall health.
research Effects of Seasonality and Pregnancy on Hair Loss and Regrowth in Rhesus Macaques
Hair loss peaks in spring and regrowth in late summer, with pregnant females losing the most hair.
research Protein Degradation: Expanding the Toolbox to Restrain Cancer Drug Resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Hypertension: Sex-Related Differences in Drug Treatment, Prevalence and Blood Pressure Control in Primary Care
Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.