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MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Finasteride works better than Permixon in reducing dihydrotestosterone levels.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.

Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Finasteride effectively treats hair loss and prostate issues with minimal side effects.

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.